Anti-Chemokine Receptor D6抗体(ab1656)
Key features and details
- Goat polyclonal to Chemokine Receptor D6
- Suitable for: IHC-P
- Reacts with: Mouse
- Isotype: IgG
概述
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产品名称
Anti-Chemokine Receptor D6抗体
参阅全部 Chemokine Receptor D6 一抗 -
描述
山羊多克隆抗体to Chemokine Receptor D6 -
宿主
Goat -
特异性
Peptide sequence is < 50 % identical to other mouse chemokine receptors in this region. -
Tested Applications & Species
Application Species IHC-P Mouse -
免疫原
Synthetic peptide:
SSSIYDYDYLDDMTILVCRKDEVLSFGRC
, corresponding to amino acids 18-45 of Mouse Chemokine Receptor D6 -
阳性对照
- Mouse spleen cells or lung.
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常规说明
Receptors for the C - C chemokine family include CCR 1, CCR 2A, CCR 3, CCR 4, CCR 5 and the Duffy blood group antigen. The C C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing the problem with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation.
One factor contributing to the crisis is the use of antibodies that are not suitable. This can lead to misleading results and the use of incorrect data informing project assumptions and direction. To help address this challenge, we have introduced an application and species grid on our primary antibody datasheets to make it easy to simplify identification of the right antibody for your needs.
Learn more here.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
Preservative: 0.1% Sodium azide
Constituent: 0.1% BSA -
Concentration information loading...
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纯度
Immunogen affinity purified -
Primary antibody说明
Receptors for the C - C chemokine family include CCR 1, CCR 2A, CCR 3, CCR 4, CCR 5 and the Duffy blood group antigen. The C C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab1656 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
应用 | Species |
---|---|
IHC-P |
Mouse
|
应用 | Ab评论 | 说明 |
---|---|---|
IHC-P |
1/250.
|
说明 |
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IHC-P
1/250. |
靶标
-
功能
Receptor for C-C type chemokines including SCYA2/MCP-1, SCY3/MIP-1-alpha, SCYA5/RANTES and SCYA7/MCP-3. -
组织特异性
Expressed primarily in placenta and fetal liver, and found at very low levels in the lung and lymph node. Found in endothelial cells lining afferent lymphatics in dermis and lymph nodes. Also found in lymph nodes subcapsular and medullary sinuses, tonsillar lymphatic sinuses and lymphatics in mucosa and submucosa of small and large intestine and appendix. Also found in some malignant vascular tumors. -
序列相似性
Belongs to the G-protein coupled receptor 1 family. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 59289 Mouse
- SwissProt: O08707 Mouse
- Unigene: 258105 Mouse
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别名
- C C chemokine receptor D6 antibody
- C-C chemokine receptor D6 antibody
- CC chemokine binding receptor JAB61 antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Chemokine Receptor D6 antibody (ab1656)ab1656, at a dilution of 1/250, staining Chemokine Receptor D6 in mouse spleen section by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Chemokine Receptor D6 antibody (ab1656)ab1656, at a dilution of 1/250, staining Chemokine Receptor D6 in mouse lung section by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Chemokine Receptor D6 antibody (ab1656)ab1656, at a dilution of 1/250, staining Chemokine Receptor D6 in mouse spleen section by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).
数据表及文件
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SDS download
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Datasheet download
文献 (4)
ab1656 被引用在 4 文献中.
- Hajrasouliha AR et al. Expression of the chemokine decoy receptor D6 mediates dendritic cell function and promotes corneal allograft rejection. Mol Vis 19:2517-25 (2013). Flow Cyt ; Mouse . PubMed: 24357920
- Besusso D et al. BDNF-TrkB signaling in striatopallidal neurons controls inhibition of locomotor behavior. Nat Commun 4:2031 (2013). IHC . PubMed: 23774276
- Wang B et al. Dlx6 regulates molecular properties of the striatum and central nucleus of the amygdala. J Comp Neurol 519:2320-34 (2011). PubMed: 21452241
- Kin NW et al. DNA Microarray Gene Expression Profile of Marginal Zone versus Follicular B Cells and Idiotype Positive Marginal Zone B Cells before and after Immunization with Streptococcus pneumoniae. J Immunol 180:6663-74 (2008). WB, Flow Cyt ; Mouse . PubMed: 18453586