重组Anti-CETP抗体[EPR13] (ab157183)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR13] to CETP
- Suitable for: WB, IP
- Reacts with: Human
Related conjugates and formulations
概述
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产品名称
Anti-CETP抗体[EPR13]
参阅全部 CETP 一抗 -
描述
兔单克隆抗体[EPR13] to CETP -
宿主
Rabbit -
经测试应用
适用于: WB, IPmore details
不适用于: ICC/IF or IHC-P -
种属反应性
与反应: Human -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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阳性对照
- Recombinant Human CETP protein (ab114408) can be used as a positive control in WB. Human plasma lysate.
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常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20ºC. -
存储溶液
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.5% BSA -
Concentration information loading...
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纯度
Protein A purified -
克隆
单克隆 -
克隆编号
EPR13 -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Positive Controls
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab157183于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
1/1000 - 1/10000. Predicted molecular weight: 55 kDa.
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|
IP |
1/10 - 1/100.
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说明 |
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WB
1/1000 - 1/10000. Predicted molecular weight: 55 kDa. |
IP
1/10 - 1/100. |
靶标
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功能
Involved in the transfer of insoluble cholesteryl esters in the reverse transport of cholesterol. -
组织特异性
Expressed by the liver and secreted in plasma. -
疾病相关
Defects in CETP are a cause of hyperalphalipoproteinemia (HYPALIP) [MIM:143470]. Affected individuals show high levels of alpha-lipoprotein (high density lipoprotein/HDL).
Defects in CETP are the cause of cholesteryl ester transfer protein deficiency (CETP deficiency) [MIM:607322]. This is an autosomal dominant condition associated with increased HDL cholesterol levels. -
序列相似性
Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. -
细胞定位
Secreted > extracellular space. - Information by UniProt
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数据库链接
- Entrez Gene: 1071 Human
- Omim: 118470 Human
- SwissProt: P11597 Human
- Unigene: 89538 Human
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别名
- BPIFF antibody
- CETP antibody
- CETP_HUMAN antibody
see all
图片
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Anti-CETP antibody [EPR13] (ab157183) at 1/1000 dilution + Human plasma lysate at 10 µg
Secondary
Goat anti-rabbit HRP at 1/2000 dilution
Predicted band size: 55 kDa -
Detection of CETP by Western Blot of Immunprecipitate. Human plasma lysates immunoprecipitated using ab157183 at 1/10 dilution.
Anti-CETP antibody [EPR13] (ab157183) at 1/1000 dilution + immunoprecipitation pellets from Human plasma at 10 µg
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab157183 被引用在 2 文献中.
- Gamache I et al. A sex-specific evolutionary interaction between ADCY9 and CETP. Elife 10:N/A (2021). PubMed: 34609279
- Zhu L et al. Expressing the Human Cholesteryl Ester Transfer Protein Minigene Improves Diet-Induced Fatty Liver and Insulin Resistance in Female Mice. Front Physiol 12:799096 (2021). PubMed: 35082691