概述

  • 产品名称
  • 描述
    兔多克隆抗体to CETP
  • 宿主
    Rabbit
  • 经测试应用
    适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 64-386 of Human CETP (Uniprot ID P11597).

  • 阳性对照
    • Molt-4, HeLa, HepG2 whole cell lysate (ab7900), DLD1 xenograft tissue

性能

应用

Our Abpromise guarantee covers the use of ab137396 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 55 kDa.
IHC-P 1/100 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能
    Involved in the transfer of insoluble cholesteryl esters in the reverse transport of cholesterol.
  • 组织特异性
    Expressed by the liver and secreted in plasma.
  • 疾病相关
    Defects in CETP are a cause of hyperalphalipoproteinemia (HYPALIP) [MIM:143470]. Affected individuals show high levels of alpha-lipoprotein (high density lipoprotein/HDL).
    Defects in CETP are the cause of cholesteryl ester transfer protein deficiency (CETP deficiency) [MIM:607322]. This is an autosomal dominant condition associated with increased HDL cholesterol levels.
  • 序列相似性
    Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
  • 细胞定位
    Secreted > extracellular space.
  • Information by UniProt
  • 数据库链接
  • 别名
    • BPIFF antibody
    • CETP antibody
    • CETP_HUMAN antibody
    • Cholesteryl ester transfer protein antibody
    • Cholesteryl ester transfer protein plasma antibody
    • HDLCQ10 antibody
    • Lipid transfer protein I antibody
    see all

图片

  • Anti-CETP antibody (ab137396) at 1/1000 dilution + Hep G2 whole cell lysate at 30 µg

    Predicted band size: 55 kDa



    10% SDS PAGE
  • Immunohistochemical analysis of paraffin embedded DLD1 xenograft tissue labelled with ab137396 at 1/500 dilution.

文献

ab137396 has not yet been referenced specifically in any publications.

客户评价及客户问答

There are currently no Customer reviews or Questions for ab137396.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册