概述

  • 产品名称
    Anti-CDKN2A/p16INK4a抗体
    参阅全部 CDKN2A/p16INK4a 一抗
  • 描述
    兔多克隆抗体to CDKN2A/p16INK4a
  • 宿主
    Rabbit
  • 经测试应用
    适用于: IHC-P, ICC/IF, IP, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment corresponding to Human CDKN2A/p16INK4a aa 8-156. (NP_000068.1).
    Sequence:

    SMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSA RVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVR DAWGRLPVDLAEELGHRDVARYLRAAAGGTRGSNHARIDAAEGPSDIPD


    Database link: P42771

  • 阳性对照
    • Human prostate tissue.

性能

应用

Our Abpromise guarantee covers the use of ab189302 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use at an assay dependent concentration.
IP Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Predicted molecular weight: 17 kDa.

靶标

  • 细胞定位
    Cytoplasmic and Nuclear
  • 数据库链接
  • 形式
    There are 4 isoforms produced by alternative splicing. Isoform 1 also known as: p16INK4a; Isoform 3 also known as: p12; Isoform 4 also known as: p14ARF; p19ARF; ARF.
  • 别名
    • CCM2 antibody
    • CDK4 inhibitor p16 INK4 antibody
    • CDK4I antibody
    • CDKN2 antibody
    • CDKN2A antibody
    • Cell cycle negative regulator beta antibody
    • CMM2 antibody
    • Cyclin dependent kinase 4 inhibitor A antibody
    • Cyclin dependent kinase inhibitor 2A (melanoma p16 inhibits CDK4) antibody
    • Cyclin Dependent Kinase Inhibitor 2A antibody
    • Cyclin dependent kinase inhibitor 2A isoform 4 antibody
    • Cyclin dependent kinase inhibitor 2A isoforms 1/2/3 antibody
    • Cyclin dependent kinase inhibitor p16 antibody
    • INK4 antibody
    • INK4A antibody
    • MLM antibody
    • MTS1 antibody
    • Multiple tumor suppressor 1 antibody
    • p14 antibody
    • p16 antibody
    • P16INK4 antibody
    • p16INK4a antibody
    • p19 antibody
    • p19Arf antibody
    • TP16 antibody
    see all

图片

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human prostate tissue labeling CDKN2A with ab189302 at 1/500 dilution, followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

文献

This product has been referenced in:
  • Tao YF  et al. Molecular mechanism of G1 arrest and cellular senescence induced by LEE011, a novel CDK4/CDK6 inhibitor, in leukemia cells. Cancer Cell Int 17:35 (2017). Read more (PubMed: 28286417) »
See 1 Publication for this product

客户评价及客户问答

There are currently no Customer reviews or Questions for ab189302.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册