Key features and details
- Rabbit polyclonal to CDC42 binding protein kinase alpha
- Suitable for: IP
- Reacts with: Human
- Isotype: IgG
产品名称Anti-CDC42 binding蛋白kinase alpha抗体
参阅全部 CDC42 binding protein kinase alpha 一抗
描述兔多克隆抗体to CDC42 binding蛋白kinase alpha
经测试应用适用于: IPmore details
预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Dog, Pig, Rhesus monkey, Gorilla, Orangutan, Elephant
Synthetic peptide, corresponding to a region between residues 1610 and 1660 of Human CDC42 binding protein kinase alpha (CAH71185.1).
- HeLa whole cell lysate.
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存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.09% Sodium azide
Constituent: Tris citrate/phosphate
Concentration information loading...
纯度Immunogen affinity purified
纯化说明ab95886 was affinity purified using an epitope specific to CDC42 binding protein kinase alpha immobilized on solid support.
The Abpromise guarantee
Use at 2-5 µg/mg of lysate.
Use at 2-5 µg/mg of lysate.
功能May act as a downstream effector of CDC42 in cytoskeletal reorganization. Contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and thus MLC2 phosphorylation.
组织特异性Abundant in the heart, brain, skeletal muscle, kidney, and pancreas, with little or no expression in the lung and liver.
序列相似性Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
Contains 1 AGC-kinase C-terminal domain.
Contains 1 CNH domain.
Contains 1 CRIB domain.
Contains 1 PH domain.
Contains 1 phorbol-ester/DAG-type zinc finger.
Contains 1 protein kinase domain.
细胞定位Cytoplasm. Displays a dispersed punctate distribution and concentrates along the cell periphery, especially at the leading edge and cell-cell junction. This concentration is PH-domain dependent.
- Information by UniProt
- A930014J19Rik antibody
- CDC42 binding protein kinase alpha (DMPK like) antibody
- CDC42 binding protein kinase alpha antibody
Detection of CDC42 binding protein kinase alpha by Western Blot of Immunprecipitate.
An other antibody at 1µg/ml staining CDC42 binding protein kinase alpha in HeLa whole cell lysate immunoprecipitated using ab95886 at 3µg/mg lysate (1 mg/IP; 20% of IP loaded/lane).
Detection: Chemiluminescence with exposure time of 10 seconds.