Anti-Cdc26 / Apc12抗体(ab96346)
Key features and details
- Rabbit polyclonal to Cdc26 / Apc12
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-Cdc26 / Apc12抗体 -
描述
兔多克隆抗体to Cdc26 / Apc12 -
宿主
Rabbit -
经测试应用
适用于: WB, ICC/IFmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Cow -
免疫原
Recombinant fragment, corresponding to a region within the N terminal amino acids 1-55 of Human Cdc26/ Apc12 (NP_644815)
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阳性对照
- 293T lysate; A431 cells for IF; H1299 whole cell lysate for WB
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab96346于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500 - 1/3000. Predicted molecular weight: 10 kDa.
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ICC/IF |
1/100 - 1/200.
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说明 |
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WB
1/500 - 1/3000. Predicted molecular weight: 10 kDa. |
ICC/IF
1/100 - 1/200. |
靶标
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相关性
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc26, a component of cell cycle anaphase-promoting complex (APC). APC is composed of a group of highly conserved proteins and functions as a cell cycle-regulated ubiquitin-protein ligase. APC thus is responsible for the cell cycle regulated proteolysis of various proteins. -
细胞定位
Nuclear -
数据库链接
- Entrez Gene: 777693 Cow
- Entrez Gene: 246184 Human
- Entrez Gene: 66440 Mouse
- Entrez Gene: 366381 Rat
- SwissProt: Q8NHZ8 Human
- SwissProt: Q99JP4 Mouse
- SwissProt: Q6YDN7 Rat
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别名
- ANAPC12 antibody
- Anaphase promoting complex subunit 12 antibody
- Anaphase promoting complex subunit CDC26 antibody
see all
图片
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab96346 被引用在 1 文献中.
- Masuda K et al. LATS1 and LATS2 phosphorylate CDC26 to modulate assembly of the tetratricopeptide repeat subcomplex of APC/C. PLoS One 10:e0118662 (2015). PubMed: 25723520