Cdc25C多肽(ab204854)
Key features and details
- Purity: > 97% HPLC
- Suitable for: HPLC, Functional Studies
描述
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产品名称
Cdc25C多肽
参阅全部 Cdc25C 蛋白酶 -
纯度
> 97 % HPLC. -
无动物成分
No -
性质
Synthetic -
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序列
KKKVSRSGLYRSPSMPENLNRPR -
氨基酸
205 to 225
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相关产品
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Recombinant Protein
- Recombinant human NUAK2 protein (ab105209)
- Recombinant human MARK4 protein (ab105211)
- Recombinant human MARK2 protein (ab119135)
- Recombinant human ARK5 protein (ab125626)
- Recombinant human BRSK2 protein (ab139629)
- Recombinant human Mark3 protein (ab60012)
- Recombinant human Chk1 protein (ab60762)
- Recombinant human Chk1 protein (ab69918)
技术指标
Our Abpromise guarantee covers the use of ab204854 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
HPLC
Functional Studies
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形式
Lyophilized -
补充说明
ab204854 (Cdc25C peptide) can be utilized as a substrate for the following active protein kinases:
ab139629 (Active human BRSK2 full length protein)
ab60762 (Active human Chk1 full length protein)
ab69918 (Active human Chk1 full length protein)
ab119135 (Active human MARK2 full length protein)
ab60012 (Active human Mark3 full length protein)
ab105211 (Active human MARK4 full length protein)
ab179497 (Active human Serine/threonine-protein kinase NIM1 full length protein)
ab125626 (Active human ARK5 full length protein)
ab105209 (Active human NUAK2 full length protein) -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Store at -20°C. Avoid freeze / thaw cycle.
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复溶Dilute peptide in distilled water to a final concentration of 1 mg/ml. For optimal storage, aliquot diluted product into smaller quantities and store at recommended temperature.
常规信息
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别名
- CDC 25
- Cdc 25C
- CDC25
see all -
功能
Functions as a dosage-dependent inducer in mitotic control. It is a tyrosine protein phosphatase required for progression of the cell cycle. It directly dephosphorylates CDK1 and activate its kinase activity. -
序列相似性
Belongs to the MPI phosphatase family.
Contains 1 rhodanese domain. -
发展阶段
Expressed predominantly in G2 phase. -
翻译后修饰
Phosphorylated by CHK1 on Ser-216. This phosphorylation creates a binding site for 14-3-3 protein and inhibits the phosphatase. Phosphorylated by PLK4. -
细胞定位
Nucleus. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (0)
ab204854 尚未被引用在任何文献中。