Key features and details
- Mouse monoclonal [1.2B6] to CD62E
- Suitable for: Flow Cyt
- Reacts with: Human, Pig
- Isotype: IgG1
参阅全部 CD62E 一抗
描述小鼠单克隆抗体[1.2B6] to CD62E
特异性This antibody recognises the human CD62E and CD62P cell surface antigens binding to a common epitope on these members of the selectin family.
经测试应用适用于: Flow Cytmore details
种属反应性与反应: Human, Pig
Human E-Selectin (ELAM-1)
This antibody inhibits neutrophil adhesion to E-selectin and to P-selectin. E-selectin (ELAM-1) is expressed on the surface of activated endothelial cells.
存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
存储溶液Preservative: 0.09% Sodium azide
Concentration information loading...
纯度Protein A purified
纯化说明Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant.
Primary antibody说明This antibody inhibits neutrophil adhesion to E-selectin and to P-selectin. E-selectin (ELAM-1) is expressed on the surface of activated endothelial cells.
Our Abpromise guarantee covers the use of ab6630 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Flow Cyt||Use a concentration of 10 µg/ml.
ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
功能Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary morphogenesis.
序列相似性Belongs to the selectin/LECAM family.
Contains 1 C-type lectin domain.
Contains 1 EGF-like domain.
Contains 6 Sushi (CCP/SCR) domains.
- Information by UniProt
- CD26E antibody
- CD62 antigen-like family member E antibody
- CD62E antibody
ab6630 被引用在 11 文献中.
- Yuan X et al. Recipient treatment with acetylcholinesterase inhibitor donepezil attenuates primary graft failure in rats through inhibiting post-transplantational donor heart ischaemia/reperfusion injury. Eur J Cardiothorac Surg 53:400-408 (2018). PubMed: 28950359
- Zhang X et al. Long Noncoding RNA Malat1 Regulates Cerebrovascular Pathologies in Ischemic Stroke. J Neurosci 37:1797-1806 (2017). PubMed: 28093478
- Zhang XJ et al. shRNAs targeting high-mobility group box-1 inhibit E-selectin expression via homeobox A9 in human umbilical vein endothelial cells. Mol Med Rep 7:1251-6 (2013). PubMed: 23403989
- Allen CL et al. Augmented dried versus cryopreserved amniotic membrane as an ocular surface dressing. PLoS One 8:e78441 (2013). PubMed: 24205233
- Zhou H et al. NAD(P)H:quinone oxidoreductase 1-compromised human bone marrow endothelial cells exhibit decreased adhesion molecule expression and CD34+ hematopoietic cell adhesion. J Pharmacol Exp Ther 334:260-8 (2010). WB ; Human . PubMed: 20378716