Key features and details
- Mouse monoclonal [MEM-118] to CD55 (PE)
- Suitable for: Flow Cyt
- Reacts with: Human, Non human primates
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgM
存放说明Shipped at 4°C. Store at +4°C.
存储溶液Preservative: 0.1% Sodium azide
Constituents: 97% PBS, 0.2% BSA
Concentration information loading...
Our Abpromise guarantee covers the use of ab130421 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Flow Cyt||Use 10µl for 106 cells. or 100µl whole blood|
功能This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.
组织特异性Expressed on the plasma membranes of all cell types that are in intimate contact with plasma complement proteins. It is also found on the surfaces of epithelial cells lining extracellular compartments, and variants of the molecule are present in body fluids and in extracellular matrix.
序列相似性Belongs to the receptors of complement activation (RCA) family.
Contains 4 Sushi (CCP/SCR) domains.
结构域The first Sushi domain (SCR1) is not necessary for function. SCR2 and SCR4 provide the proper conformation for the active site on SCR3.
翻译后修饰The Ser/Thr-rich domain is heavily O-glycosylated.
- Information by UniProt
- CD 55 antibody
- CD55 antibody
- CD55 antigen antibody