Key features and details
- Mouse monoclonal [UCHM1] to CD14
- Suitable for: Flow Cyt
- Reacts with: Human, Cynomolgus monkey, Rhesus monkey
- Isotype: IgG2a
参阅全部 CD14 一抗
描述小鼠单克隆抗体[UCHM1] to CD14
特异性ab6623 recognises a monocyte surface antigen of 55 kDa found chiefly on monocytes. UCHM1 was clustered at the Third International Workshop and Conference on Human Leucocyte Differentiation Antigens. Oxford 1986, as CDw14, group A. In tonsil tissue sections UCHM1 gives positive staining reactions with monocytic cells, the interfollicular tissue macrophages seen under the capsule, and dendritic reticulum cells. Skin Langerhans cells are always negative. UCHM1 also reacts with Kupffer cells and sinus lining cells on the liver.
经测试应用适用于: Flow Cytmore details
种属反应性与反应: Human, Cynomolgus monkey, Rhesus monkey
Human Thymocytes followed by peripheral blood mononuclear cells
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存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.09% Sodium azide
Concentration information loading...
纯度Protein G purified
纯化说明Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant.
Our Abpromise guarantee covers the use of ab6623 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Flow Cyt||Use at an assay dependent concentration.
ab170191 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
功能Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.
组织特异性Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages.
序列相似性Contains 11 LRR (leucine-rich) repeats.
翻译后修饰N- and O- glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan.
- Information by UniProt
- CD 14 antibody
- CD_antigen=CD14 antibody
- CD14 antibody