Anti-CD10抗体[FR4D11/F3] (Phycoerythrin) (ab1165)
概述
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产品名称
Anti-CD10抗体[FR4D11/F3] (Phycoerythrin)
参阅全部 CD10 一抗 -
描述
小鼠单克隆抗体[FR4D11/F3] to CD10 (Phycoerythrin) -
宿主
Mouse -
偶联物
Phycoerythrin. Ex: 488nm, Em: 575nm -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Human
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
Preservative: 0.1% Sodium azide
Constituent: 0.5% BSA -
Concentration information loading... -
克隆
单克隆 -
克隆编号
FR4D11/F3 -
骨髓瘤
unknown -
同种型
IgG1 -
轻链类型
unknown -
研究领域
相关产品
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Isotype control
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Recombinant Protein
应用
Our Abpromise guarantee covers the use of ab1165 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Flow Cyt |
应用说明
Characterization of leukaemias and lymphomas in human lysed whole peripheral blood or mononuclear cells separated by density gradient.
Childhood ALL prognosis (patients CD10+ have a better prognosis than CD10-).
CD10 (PE) immunofluorescence analysis can be performed on a flow cytometerequipped with an excitation source of 488nm and fitted with logarithmic amplifiers.
10µl ofCD10 (PE) is sufficient for labelling of 1x106 cells.
Molecular F/P ratio: 1.0
Childhood ALL prognosis (patients CD10+ have a better prognosis than CD10-).
CD10 (PE) immunofluorescence analysis can be performed on a flow cytometerequipped with an excitation source of 488nm and fitted with logarithmic amplifiers.
10µl ofCD10 (PE) is sufficient for labelling of 1x106 cells.
Molecular F/P ratio: 1.0
靶标
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功能
Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers. -
序列相似性
Belongs to the peptidase M13 family. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 4311 Human
- Omim: 120520 Human
- SwissProt: P08473 Human
- Unigene: 307734 Human
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别名
- Atriopeptidase antibody
- CALLA antibody
- CD10 antibody
see all
文献
This product has been referenced in:
- Husak Z & Dworzak MN CD99 ligation upregulates HSP70 on acute lymphoblastic leukemia cells and concomitantly increases NK cytotoxicity. Cell Death Dis 3:e425 (2012). Flow Cyt ; Human . Read more (PubMed: 23152061) »
- Ferletta M et al. Canine mammary tumors contain cancer stem-like cells and form spheroids with an embryonic stem cell signature. Int J Dev Biol 55:791-9 (2011). Read more (PubMed: 22161835) »
