Key features and details
- Goat polyclonal to CCR3
- Suitable for: ICC
- Reacts with: Human
- Isotype: IgG
参阅全部 CCR3 一抗
特异性Peptide sequence is < 50 % identical to other human chemokine receptors in this region.
经测试应用适用于: ICCmore details
Human CCR 3 is a receptor for CC chemokine eotaxin-1 and eotaxin-2. CCR 3 is constitutively expressed on eosinophils, small intestine and colon. The human CCR 3 protein contains 356 amino acids.
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存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.1% Sodium azide
Constituents: 0.1% BSA, 0.11% Dibasic monohydrogen potassium phosphate, 0.05% Monobasic dihydrogen potassium phosphate, 0.82% Sodium chloride
Concentration information loading...
纯度Immunogen affinity purified
Primary antibody说明Human CCR 3 is a receptor for CC chemokine eotaxin-1 and eotaxin-2. CCR 3 is constitutively expressed on eosinophils, small intestine and colon. The human CCR 3 protein contains 356 amino acids.
Our Abpromise guarantee covers the use of ab1667 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
功能Receptor for a C-C type chemokine. Binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES and MIP-1 delta. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection.
组织特异性In eosinophils as well as trace amounts in neutrophils and monocytes.
序列相似性Belongs to the G-protein coupled receptor 1 family.
- Information by UniProt
- B chemokine receptor antibody
- b-chemokine receptor antibody
- C C chemokine receptor type 3 antibody
ab1667 被引用在 19 文献中.
- Venugopal N et al. The primary cilium dampens proliferative signaling and represses a G2/M transcriptional network in quiescent myoblasts. BMC Mol Cell Biol 21:25 (2020). PubMed: 32293249
- Jäger K et al. Expression of Neural Crest Markers GLDC and ERRFI1 is Correlated with Melanoma Prognosis. Cancers (Basel) 11:N/A (2019). PubMed: 30641895
- Saito Y et al. Synbiotics suppress colitis-induced tumorigenesis in a colon-specific cancer mouse model. PLoS One 14:e0216393 (2019). PubMed: 31242213
- Han Y et al. IL-38 Ameliorates Skin Inflammation and Limits IL-17 Production from ?d T Cells. Cell Rep 27:835-846.e5 (2019). PubMed: 30995480
- Shoemaker RH et al. Evaluation of the STAT3 inhibitor GLG-302 for the prevention of estrogen receptor-positive and -negative mammary cancers. Oncol Rep 42:1205-1213 (2019). PubMed: 31322250