Anti-CCDC106抗体(ab105354)
Key features and details
- Rabbit polyclonal to CCDC106
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-CCDC106抗体 -
描述
兔多克隆抗体to CCDC106 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide, 15 amino acid, from within the region of the C-terminus of Human CCDC106 (NP_037433).
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阳性对照
- WB: Human brain tissue lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab105354于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 32 kDa.
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说明 |
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WB
Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 32 kDa. |
靶标
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功能
Promotes the degradation of p53/TP53 protein and inhibits its transactivity. -
细胞定位
Nucleus. Colocalizes with p53/TP53. - Information by UniProt
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数据库链接
- Entrez Gene: 29903 Human
- Omim: 613478 Human
- SwissProt: Q9BWC9 Human
- Unigene: 82482 Human
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别名
- CC106_HUMAN antibody
- Ccdc106 antibody
- Coiled-coil domain-containing protein 106 antibody
see all
图片
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab105354 被引用在 3 文献中.
- Zhao N et al. CCDC106 promotes the proliferation and invasion of ovarian cancer cells by suppressing p21 transcription through a p53-independent pathway. Bioengineered 13:10956-10972 (2022). PubMed: 35484984
- Zhang X et al. CCDC106 promotes non-small cell lung cancer cell proliferation. Oncotarget 8:26662-26670 (2017). PubMed: 28460455
- Wang ZS et al. MicroRNA-187 inhibits tumor growth and invasion by directly targeting CD276 in colorectal cancer. Oncotarget 7:44266-44276 (2016). PubMed: 27329595