Anti-CARD9抗体(ab115578)
Key features and details
- Rabbit polyclonal to CARD9
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-CARD9抗体
参阅全部 CARD9 一抗 -
描述
兔多克隆抗体to CARD9 -
宿主
Rabbit -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Horse, Dog -
免疫原
Synthetic peptide:
DRENTTGSDNTDTEGS
conjugated to KLH, corresponding to amino acids 521-536 of Human CARD9 (NP_434700.2). -
阳性对照
- Human adrenal tissue.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -80°C. -
存储溶液
pH: 7.4
Preservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab115578于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
IHC-P |
Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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说明 |
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IHC-P
Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
靶标
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功能
Activates NF-kappa-B via BCL10. -
组织特异性
Highly expressed in spleen. Also detected in liver, placenta, lung, peripheral blood leukocytes and in brain. -
疾病相关
Defects in CARD9 are the cause of familial candidiasis type 2 (CANDF2) [MIM:212050]. Chronic mucocutaneous candidiasis is characterized by impaired clearance of fungal infections and results in colonization and infections of the mucosa or skin, predominantly with Candida albicans. CANDF2 is an autosomal recessive chronic mucocutaneous candidiasis. -
序列相似性
Contains 1 CARD domain. -
细胞定位
Cytoplasm. - Information by UniProt
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数据库链接
- Entrez Gene: 64170 Human
- Entrez Gene: 332579 Mouse
- Entrez Gene: 64171 Rat
- Omim: 607212 Human
- SwissProt: Q9H257 Human
- SwissProt: Q9EPY0 Rat
- Unigene: 694071 Human
- Unigene: 64486 Rat
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别名
- CANDF2 antibody
- CARD9 antibody
- CARD9_HUMAN antibody
see all
图片
数据表及文件
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Datasheet download
文献 (1)
ab115578 被引用在 1 文献中.
- Sekino N et al. Caspase recruitment domain family member 9 expression is a promising biomarker in esophageal squamous cell carcinoma. Ann Gastroenterol Surg 4:135-141 (2020). PubMed: 32258978