Anti-Cannabinoid Receptor I抗体(ab3558)
Key features and details
- Rabbit polyclonal to Cannabinoid Receptor I
- Suitable for: ICC/IF
- Reacts with: Mouse, Rat, Rabbit, Human, Ferret
- Isotype: IgG
概述
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产品名称
Anti-Cannabinoid Receptor I抗体
参阅全部 Cannabinoid Receptor I 一抗 -
描述
兔多克隆抗体to Cannabinoid Receptor I -
宿主
Rabbit -
特异性
Detects CB1 from Human and Rat tissues as well as transfected Rat CB1. -
经测试应用
适用于: ICC/IFmore details -
种属反应性
与反应: Mouse, Rat, Rabbit, Human, Ferret
预测可用于: Cat, Chimpanzee, Rhesus monkey -
免疫原
Fusion protein corresponding to Human Cannabinoid Receptor I aa 1-99 (N terminal).
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常规说明
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Preservative: 0.05% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 0.1% BSA, 49% PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
Our Abpromise guarantee covers the use of ab3558 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
应用 | Ab评论 | 说明 |
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ICC/IF | Use at an assay dependent concentration. |
靶标
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功能
Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current. Isoform 2 and isoform 3 have altered ligand binding. -
组织特异性
Widely expressed. -
序列相似性
Belongs to the G-protein coupled receptor 1 family. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 1268 Human
- Entrez Gene: 12801 Mouse
- Entrez Gene: 25248 Rat
- Omim: 114610 Human
- SwissProt: O02777 Cat
- SwissProt: Q5IS73 Chimpanzee
- SwissProt: P21554 Human
- SwissProt: P47746 Mouse
see all -
别名
- CANN6 antibody
- Cannabinoid receptor 1 antibody
- CB-R antibody
see all
图片
实验方案
数据表及文件
文献 (3)
ab3558 被引用在 3 文献中.
- Kleyer J et al. Cannabinoid receptor trafficking in peripheral cells is dynamically regulated by a binary biochemical switch. Biochem Pharmacol 83:1393-412 (2012). Flow Cyt, IP ; Human . PubMed: 22387618
- Shen L et al. The role of peripheral cannabinoid receptors type 1 in rats with visceral hypersensitivity induced by chronic restraint stress. J Neurogastroenterol Motil 16:281-90 (2010). WB ; Rat . PubMed: 20680167
- Leonti M et al. Falcarinol is a covalent cannabinoid CB1 receptor antagonist and induces pro-allergic effects in skin. Biochem Pharmacol 79:1815-26 (2010). WB, Flow Cyt ; Human . PubMed: 20206138