Anti-Cannabinoid Receptor I抗体(ab3558)
Key features and details
- Rabbit polyclonal to Cannabinoid Receptor I
- Suitable for: ICC/IF
- Reacts with: Rat
- Isotype: IgG
概述
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产品名称
Anti-Cannabinoid Receptor I抗体
参阅全部 Cannabinoid Receptor I 一抗 -
描述
兔多克隆抗体to Cannabinoid Receptor I -
宿主
Rabbit -
特异性
Detects CB1 from Human and Rat tissues as well as transfected Rat CB1. -
经测试应用
适用于: ICC/IFmore details -
种属反应性
与反应: Rat
预测可用于: Cat, Chimpanzee, Rhesus monkey -
免疫原
Fusion protein corresponding to Human Cannabinoid Receptor I aa 1-99 (N terminal).
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Preservative: 0.05% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 0.1% BSA, 49% PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
应用 | Ab评论 | 说明 |
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ICC/IF |
Use at an assay dependent concentration.
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说明 |
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ICC/IF
Use at an assay dependent concentration. |
靶标
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功能
Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current. Isoform 2 and isoform 3 have altered ligand binding. -
组织特异性
Widely expressed. -
序列相似性
Belongs to the G-protein coupled receptor 1 family. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 25248 Rat
- SwissProt: O02777 Cat
- SwissProt: Q5IS73 Chimpanzee
- SwissProt: P20272 Rat
- SwissProt: Q71SP5 Rhesus monkey
- Unigene: 222240 Rat
- Unigene: 89774 Rat
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别名
- CANN6 antibody
- Cannabinoid receptor 1 antibody
- CB-R antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab3558 被引用在 3 文献中.
- Kleyer J et al. Cannabinoid receptor trafficking in peripheral cells is dynamically regulated by a binary biochemical switch. Biochem Pharmacol 83:1393-412 (2012). Flow Cyt, IP ; Human . PubMed: 22387618
- Shen L et al. The role of peripheral cannabinoid receptors type 1 in rats with visceral hypersensitivity induced by chronic restraint stress. J Neurogastroenterol Motil 16:281-90 (2010). WB ; Rat . PubMed: 20680167
- Leonti M et al. Falcarinol is a covalent cannabinoid CB1 receptor antagonist and induces pro-allergic effects in skin. Biochem Pharmacol 79:1815-26 (2010). WB, Flow Cyt ; Human . PubMed: 20206138