Anti-Calcium binding蛋白P22抗体(ab96203)
Key features and details
- Rabbit polyclonal to Calcium binding protein P22
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-Calcium binding蛋白P22抗体
参阅全部 Calcium binding protein P22 一抗 -
描述
兔多克隆抗体to Calcium binding蛋白P22 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Cow -
免疫原
Synthetic peptide, corresponding to a region within amino acids 47-111 of Human Calcium binding protein P22.
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阳性对照
- HepG2 cells
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab96203于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500 - 1/3000. Predicted molecular weight: 22 kDa.
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说明 |
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WB
1/500 - 1/3000. Predicted molecular weight: 22 kDa. |
靶标
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功能
Required for constitutive membrane traffic. Inhibits GTPase-stimulated Na(+)/H(+) exchange. Also inhibits calcineurin phosphatase activity. Required for activity of SLC9A1/NHE1. -
组织特异性
Ubiquitously expressed. Has been found in fetal eye, lung, liver, muscle, heart, kidney, thymus and spleen. -
序列相似性
Contains 4 EF-hand domains. -
翻译后修饰
Both N-myristoylation and calcium-mediated conformational changes are essential for its function in exocytic traffic.
Phosphorylated; decreased phosphorylation is associated with an increase in exchange activity. The phosphorylation state may regulate the binding to NHE1. -
细胞定位
Cytoplasm. - Information by UniProt
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数据库链接
- Entrez Gene: 512662 Cow
- Entrez Gene: 11261 Human
- Entrez Gene: 56398 Mouse
- Omim: 606988 Human
- SwissProt: Q3SYS6 Cow
- SwissProt: Q99653 Human
- SwissProt: P61022 Mouse
- Unigene: 406234 Human
see all -
别名
- Calcineurin B homolog antibody
- Calcineurin B homologous protein antibody
- Calcineurin homologous protein antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab96203 尚未被引用在任何文献中。