概述

  • 产品名称
    BrdU (5-bromo-2'-deoxyuridine),Thymidine analog
  • 描述
    Thymidine analog for measuring cell proliferation
  • 生物学描述

    Thymidine analog, naturally incorporates into proliferating cells. Labels DNA, useful marker for study of DNA synthesis. Decreases TTP pools in vitro. Antitumor and radiation-sensitizing agent. Active in vitro and in vivo.

  • 纯度
    > 98%
  • 常规说明

    Unstained control slides from mice treated with BrdU (formalin-fixed, paraffin-embedded intestine sections) are available as BrdU control slides ab129956

  • CAS编号
    59-14-3
  • 化学结构
    Chemical Structure

性能

图片

  • Estimation of S-phase Duration using EdU-BrdU Dual Pulse Labelling.

    (From Figure 5A of Massey)

文献

This product has been referenced in:
  • Takagi S  et al. Detection of 5-bromo-2-deoxyuridine (BrdUrd) incorporation with monoclonal anti-BrdUrd antibody after deoxyribonuclease treatment. Cytometry 14:640-8 (1993). Read more (PubMed: 8404370) »
  • Shewach DS  et al. Decrease in TTP pools mediated by 5-bromo-2'-deoxyuridine exposure in a human glioblastoma cell line. Biochem Pharmacol 43:1579-85 (1992). Read more (PubMed: 1567479) »
  • Brennan LM  et al. An in vivo method for using 5-bromo-2'-deoxyuridine (BrdU) as a marker of chemically-induced hepatocellular proliferation in the Japanese medaka (Oryzias latipes). Toxicol Pathol 29:387-97 (0). Read more (PubMed: 11442025) »
See all 9 Publications for this product

客户评价及客户问答

Abreviews
It works very well. The complementary protocol on the Abcam website is straightforward and easy to follow.
I used it at the concentration of 10 micromolar and left for 2 hours in culture.

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Verified customer

提交于 Nov 27 2017

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