Anti-BPOZ/ABTB1抗体(ab1077)
Key features and details
- Goat polyclonal to BPOZ/ABTB1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-BPOZ/ABTB1抗体 -
描述
山羊多克隆抗体to BPOZ/ABTB1 -
宿主
Goat -
Tested Applications & Species
See all applications and species dataApplication Species WB Human
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免疫原
Synthetic peptide corresponding to Human BPOZ/ABTB1 aa 323-336 (N terminal).
Sequence:RALEDLLVSIGLDC
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常规说明
This product was previously labelled as BPOZ
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing the problem with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation.
One factor contributing to the crisis is the use of antibodies that are not suitable. This can lead to misleading results and the use of incorrect data informing project assumptions and direction. To help address this challenge, we have introduced an application and species grid on our primary antibody datasheets to make it easy to simplify identification of the right antibody for your needs.
Learn more here.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.30
Constituent: 0.5% BSA -
Concentration information loading... -
纯度
Immunogen affinity purified -
纯化说明
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab1077 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
| 应用 | Species |
|---|---|
| WB |
Human
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| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 40 kDa (predicted molecular weight: 39 kDa).
1 hour primary incubation is recommended for this product. |
| 说明 |
|---|
|
WB
Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 40 kDa (predicted molecular weight: 39 kDa). 1 hour primary incubation is recommended for this product. |
靶标
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功能
May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes. -
组织特异性
Ubiquitously expressed in all fetal tissues examined including heart, brain, liver, and kidney. Also expressed at lower levels in both adult heart and hypertrophic heart. -
序列相似性
Contains 2 ANK repeats.
Contains 2 BTB (POZ) domains. -
细胞定位
Cytoplasm. - Information by UniProt
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数据库链接
- Entrez Gene: 80325 Human
- Omim: 608308 Human
- SwissProt: Q969K4 Human
- Unigene: 107812 Human
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别名
- ABTB 1 antibody
- Abtb1 antibody
- ABTB1_HUMAN antibody
see all
图片
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Western blot - Anti-BPOZ/ABTB1 antibody (ab1077)
ab1077 at a concentration of 0.2µg/ml staining approximately 40kDa BPOZ/ABTB1 in human brain extract (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
ab1077 at a concentration of 0.2µg/ml staining approximately 40kDa BPOZ/ABTB1 in human brain extract (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab1077 被引用在 1 文献中.
- Roy A & Pahan K Ankyrin repeat and BTB/POZ domain containing protein-2 inhibits the aggregation of alpha-synuclein: Implications for Parkinson's disease. FEBS Lett 587:3567-74 (2013). ICC/IF ; Mouse . PubMed: 24076025