重组生物素Anti-beta Actin抗体[RM112] - N-terminal (ab222760)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Biotin Rabbit monoclonal [RM112] to beta Actin - N-terminal
- Suitable for: ICC/IF, WB
- Reacts with: Human
- Conjugation: Biotin
概述
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产品名称
生物素Anti-beta Actin抗体[RM112] - N-terminal
参阅全部 beta Actin 一抗 -
描述
生物素兔单克隆抗体[RM112] to beta Actin - N-terminal -
宿主
Rabbit -
偶联物
Biotin -
特异性
No cross reactivity with other isoforms of Actin. -
经测试应用
适用于: ICC/IF, WBmore details -
种属反应性
与反应: Human
预测可用于: a wide range of other species -
免疫原
Synthetic peptide corresponding to beta Actin (N terminal).
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阳性对照
- ICC/IF: HeLa (human epithelial cell line from cervix adenocarcinoma) cells. WB: A431 (human epidermoid carcinoma cell line) cells.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. Store In the Dark. -
存储溶液
Preservative: 0.09% Sodium azide
Constituents: 1% BSA, 50% Glycerol (glycerin, glycerine) -
Concentration information loading...
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纯度
Protein A purified -
克隆
单克隆 -
克隆编号
RM112 -
同种型
IgG -
研究领域
相关产品
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab222760于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
ICC/IF |
1/200.
|
|
WB |
1/1000.
|
说明 |
---|
ICC/IF
1/200. |
WB
1/1000. |
靶标
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功能
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. -
疾病相关
Defects in ACTB are a cause of dystonia juvenile-onset (DYTJ) [MIM:607371]. DYTJ is a form of dystonia with juvenile onset. Dystonia is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. DYTJ patients manifest progressive, generalized, dopa-unresponsive dystonia, developmental malformations and sensory hearing loss. -
序列相似性
Belongs to the actin family. -
翻译后修饰
ISGylated. -
细胞定位
Cytoplasm > cytoskeleton. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. - Information by UniProt
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数据库链接
- Entrez Gene: 60 Human
- Omim: 102630 Human
- SwissProt: P60709 Human
- Unigene: 520640 Human
- Unigene: 708120 Human
- Unigene: 727576 Human
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别名
- A26C1A antibody
- A26C1B antibody
- ACTB antibody
see all
图片
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab222760 尚未被引用在任何文献中。