Anti-BD-3抗体(ab19270)
Key features and details
- Rabbit polyclonal to BD-3
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-BD-3抗体
参阅全部 BD-3 一抗 -
描述
兔多克隆抗体to BD-3 -
宿主
Rabbit -
经测试应用
适用于: WB, ICC/IFmore details -
种属反应性
与反应: Human -
免疫原
Recombinant full length protein corresponding to Human BD-3.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab19270于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use at an assay dependent concentration.
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ICC/IF |
Use at an assay dependent concentration. PubMed: 23627872
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说明 |
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WB
Use at an assay dependent concentration. |
ICC/IF
Use at an assay dependent concentration. PubMed: 23627872 |
靶标
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功能
Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistent E.faecium. No significant hemolytic activity was observed. -
组织特异性
Highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. Low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine. -
序列相似性
Belongs to the beta-defensin family. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 414325 Human
- Entrez Gene: 55894 Human
- SwissProt: P81534 Human
- Unigene: 283082 Human
- Unigene: 637221 Human
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别名
- BD 3 antibody
- BD-3 antibody
- BD3 antibody
see all
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (11)
ab19270 被引用在 11 文献中.
- Sun J et al. Growth differentiation factor 11 accelerates liver senescence through the inhibition of autophagy. Aging Cell 21:e13532 (2022). PubMed: 34905649
- Šerstņova K et al. Expression of anti-inflammatory markers IL-2, IL-10, TGF-β1, βDEF-2, βDEF-3 and Cathelicidin LL37 in dairy cattle milk with different health status of the udder. Pol J Vet Sci 25:237-248 (2022). PubMed: 35861957
- Li L et al. Gold Nanoparticles Combined Human ß-Defensin 3 Gene-Modified Human Periodontal Ligament Cells Alleviate Periodontal Destruction via the p38 MAPK Pathway. Front Bioeng Biotechnol 9:631191 (2021). PubMed: 33585435
- Boer DEC et al. Skin of atopic dermatitis patients shows disturbed ß-glucocerebrosidase and acid sphingomyelinase activity that relates to changes in stratum corneum lipid composition. Biochim Biophys Acta Mol Cell Biol Lipids 1865:158673 (2020). PubMed: 32092464
- Li L et al. Human ß-defensin 3 gene modification promotes the osteogenic differentiation of human periodontal ligament cells and bone repair in periodontitis. Int J Oral Sci 12:13 (2020). PubMed: 32350241