Anti-ATPBD3抗体(ab136083)
Key features and details
- Rabbit polyclonal to ATPBD3
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-ATPBD3抗体
参阅全部 ATPBD3 一抗 -
描述
兔多克隆抗体to ATPBD3 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide derived from the C terminal region of Human ATPBD3.
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阳性对照
- 293 cell lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20ºC. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 0.88% Sodium chloride, 50% Glycerol (glycerin, glycerine)
PBS without Mg2+ and Ca2+ -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab136083于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500 - 1/1000. Predicted molecular weight: 36 kDa.
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说明 |
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WB
1/500 - 1/1000. Predicted molecular weight: 36 kDa. |
靶标
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功能
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. -
通路
tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis. -
序列相似性
Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily. -
细胞定位
Cytoplasm. - Information by UniProt
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数据库链接
- Entrez Gene: 90353 Human
- Omim: 612694 Human
- SwissProt: Q7Z7A3 Human
- Unigene: 148425 Human
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别名
- ATP binding domain 3 antibody
- ATP-binding domain-containing protein 3 antibody
- Cancer associated protein antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab136083 被引用在 2 文献中.
- Trzaska C et al. 2,6-Diaminopurine as a highly potent corrector of UGA nonsense mutations. Nat Commun 11:1509 (2020). PubMed: 32198346
- Xu S et al. Genome-wide CRISPR screen identifies ELP5 as a determinant of gemcitabine sensitivity in gallbladder cancer. Nat Commun 10:5492 (2019). PubMed: 31792210