Anti-ARS2抗体(ab88392)
Key features and details
- Mouse polyclonal to ARS2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-ARS2抗体
参阅全部 ARS2 一抗 -
描述
小鼠多克隆抗体to ARS2 -
宿主
Mouse -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Partial protein corresponding to amino acids 80 - 876 of human ARS2 (Swissprot id Q9BXP5).
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阳性对照
- Human pancreas tissue lysate, Jurkat cell lysate and ARS2 transfected 293T cell lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.40
Constituent: 100% PBS -
Concentration information loading...
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纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab88392于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 101 kDa.
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说明 |
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WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 101 kDa. |
靶标
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功能
Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA); however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity. -
组织特异性
Ubiquitously expressed. -
序列相似性
Belongs to the ARS2 family. -
细胞定位
Nucleus > nucleoplasm. Cytoplasm. Predominantly nuclear. Shuttles between the nucleus and the cytoplasm in a CRM1-dependent way. - Information by UniProt
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数据库链接
- Entrez Gene: 51593 Human
- Omim: 614469 Human
- SwissProt: Q9BXP5 Human
- Unigene: 111801 Human
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别名
- ARS2 protein antibody
- Arsenate resistance protein ARS2 antibody
- Arsenite resistance protein 2 antibody
see all
图片
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Anti-ARS2 antibody (ab88392) at 1 µg/ml + human pancreas tissue lysate at 50 µg
Predicted band size: 101 kDa
Observed band size: 99 kDa why is the actual band size different from the predicted? -
Anti-ARS2 antibody (ab88392) at 1 µg/ml + Jurkat cell lysate at 50 µg
Predicted band size: 101 kDa -
All lanes : Anti-ARS2 antibody (ab88392) at 1 µg/ml
Lane 1 : ARS2 transfected 293T cell lysate
Lane 2 : Non transfected 293T cell lysate
Lysates/proteins at 50 µg per lane.
Predicted band size: 101 kDa
Observed band size: 101 kDa
数据表及文件
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Datasheet download
文献 (0)
ab88392 尚未被引用在任何文献中。