产品名称Anti-Aromatase抗体[EPR4534(2)] - BSA and Azide free
参阅全部 Aromatase 一抗
描述兔单克隆抗体[EPR4534(2)] to Aromatase - BSA and Azide free
经测试应用适用于: IP, WBmore details
种属反应性与反应: Rat, Human
Synthetic peptide within Human Aromatase aa 1-100. The exact sequence is proprietary.
(Peptide available as
- WB: Rat brain lysate.
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents
This product is a recombinant rabbit monoclonal antibody.
存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Concentration information loading...
纯度Protein A purified
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipid metabolism
Immunizing Peptide (Blocking)
Our Abpromise guarantee covers the use of ab236052 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IP||Use at an assay dependent concentration.|
|WB||Use at an assay dependent concentration. Detects a band of approximately 53 kDa (predicted molecular weight: 58 kDa).Can be blocked with Aromatase peptide (ab186919).|
功能Catalyzes the formation of aromatic C18 estrogens from C19 androgens.
组织特异性Brain, placenta and gonads.
疾病相关Defects in CYP19A1 are a cause of aromatase excess syndrome (AEXS) [MIM:139300]; also known as familial gynecomastia. AEXS is characterized by an estrogen excess due to an increased aromatase activity.
Defects in CYP19A1 are the cause of aromatase deficiency (AROD) [MIM:107910]. AROD is a rare disease in which fetal androgens are not converted into estrogens due to placental aromatase deficiency. Thus, pregnant women exhibit a hirsutism, which spontaneously resolves after post-partum. At birth, female babies present with pseudohermaphroditism due to virilization of extern genital organs. In adult females, manifestations include delay of puberty, breast hypoplasia and primary amenorrhoea with multicystic ovaries.
序列相似性Belongs to the cytochrome P450 family.
- Information by UniProt
- ARO antibody
- ARO1 antibody
- Aromatase antibody
Anti-Aromatase antibody [EPR4534(2)] (ab124776) at 1/2000 dilution + Rat brain tissue lysate at 20 µg
HRP-conjugated anti-rabbit IgG, specific to the non-reduced form of IgG at 1/5000 dilution
Predicted band size: 58 kDa
Observed band size: 53 kDa why is the actual band size different from the predicted?
Blocking and dilution buffer: 5% NFDM/TBST
This data was developed using the same antibody clone in a different buffer formulation containing PBS, BSA, glycerol, and sodium azide (ab124776).
ab236052 has not yet been referenced specifically in any publications.