Anti-AP3抗体(ab3705)
Key features and details
- Goat polyclonal to AP3
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-AP3抗体
参阅全部 AP3 一抗 -
描述
山羊多克隆抗体to AP3 -
宿主
Goat -
特异性
Recognises a strong band at 130kD representing AP3. Also detects a band at about 80kD probably representing non-specific binding. -
Tested Applications & Species
Application Species WB Human -
免疫原
Synthetic peptide:
SPSPQKRYQDTPGC
, corresponding to amino acids 686-698 of Human AP3. -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing the problem with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation.
One factor contributing to the crisis is the use of antibodies that are not suitable. This can lead to misleading results and the use of incorrect data informing project assumptions and direction. To help address this challenge, we have introduced an application and species grid on our primary antibody datasheets to make it easy to simplify identification of the right antibody for your needs.
Learn more here.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Preservative: 0.01% Sodium azide
Constituents: 0.42% Potassium phosphate, 0.87% Sodium chloride -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab3705 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
应用 | Species |
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WB |
Human
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应用 | Ab评论 | 说明 |
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WB |
1/500. Detects a band of approximately 130 kDa (predicted molecular weight: 130 kDa).
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说明 |
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WB
1/500. Detects a band of approximately 130 kDa (predicted molecular weight: 130 kDa). |
靶标
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功能
Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. -
组织特异性
Present in all adult tissues examined with the highest levels in skeletal muscle, heart, pancreas and testis. -
序列相似性
Belongs to the adaptor complexes large subunit family.
Contains 11 HEAT repeats. -
细胞定位
Cytoplasm. Golgi apparatus membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 8943 Human
- Omim: 607246 Human
- SwissProt: O14617 Human
- Unigene: 512815 Human
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别名
- Adapter-related protein complex 3 subunit delta-1 antibody
- adaptor-related protein complex 3, delta 1 subunit antibody
- ADTD antibody
see all
图片
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Western blot using ab3705 on HeLa whole cell extract at 1/500.
Secondary ab: Rabbit polyclonal to Goat IgG (HRP)
ab6741 (1/5000)
Exposure time: 30 seconds.
Lysate at 20 g/lane.µ Predicted molecular weight:130 kDa. The band at about 80kD probably represents non-specific binding.
Secondary ab: Rabbit polyclonal to Goat IgG (HRP) ab6741 (1/5000)
Exposure time: 30 seconds.
Lysate at 20µg/lane.
Predicted molecular weight:130 kDa. The band at about 80kD probably represents non-specific binding.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab3705 尚未被引用在任何文献中。