Anti-AP1S2抗体(ab97590)
Key features and details
- Rabbit polyclonal to AP1S2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-AP1S2抗体
参阅全部 AP1S2 一抗 -
描述
兔多克隆抗体to AP1S2 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Cow, Zebrafish
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免疫原
Recombinant fragment containing a sequence corresponding to a region within amino acids 1-122 of Human AP1S2 (NP_003907).
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阳性对照
- Raji whole cell lysate; A431 cell lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab97590于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/500 - 1/3000. Predicted molecular weight: 19 kDa.
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| 说明 |
|---|
|
WB
1/500 - 1/3000. Predicted molecular weight: 19 kDa. |
靶标
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功能
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. -
组织特异性
Widely expressed. -
疾病相关
Defects in AP1S2 are the cause of mental retardation X-linked type 59 (MRX59) [MIM:300630]. It is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. In contrast to syndromic or specific X-linked mental retardation which also present with associated physical, neurological and/or psychiatric manifestations, intellectual deficiency is the only primary symptom of non-syndromic X-linked mental retardation. MRX59 consists of a mild-to-profound mental retardation. Other features includes hypotonia early in life and delay in walking. -
序列相似性
Belongs to the adaptor complexes small subunit family. -
细胞定位
Golgi apparatus. Cytoplasmic vesicle membrane. Membrane > clathrin-coated pit. Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex. - Information by UniProt
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数据库链接
- Entrez Gene: 8905 Human
- Entrez Gene: 108012 Mouse
- Entrez Gene: 327237 Zebrafish
- Omim: 300629 Human
- SwissProt: P56377 Human
- SwissProt: Q9DB50 Mouse
- Unigene: 653504 Human
- Unigene: 720688 Human
see all -
别名
- Adapter related protein complex 1 sigma 1B subunit antibody
- Adapter-related protein complex 1 sigma-1B subunit antibody
- Adaptor protein complex AP 1 sigma 1B subunit antibody
see all
图片
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Western blot - Anti-AP1S2 antibody (ab97590)Anti-AP1S2 antibody (ab97590) at 1/1000 dilution + Raji whole cell lysate at 30 µg
Predicted band size: 19 kDa
12% SDS-PAGE
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab97590 尚未被引用在任何文献中。