Anti-ALDH1L1抗体- Astrocyte Marker (ab190298)
Key features and details
- Rabbit polyclonal to ALDH1L1 - Astrocyte Marker
- Suitable for: WB, ICC/IF
- Reacts with: Rat, Human
- Isotype: IgG
概述
-
产品名称
Anti-ALDH1L1抗体- Astrocyte Marker
参阅全部 ALDH1L1 一抗 -
描述
兔多克隆抗体to ALDH1L1 - Astrocyte Marker -
宿主
Rabbit -
经测试应用
适用于: WB, ICC/IFmore details -
种属反应性
与反应: Rat, Human
预测可用于: Orangutan -
免疫原
Recombinant full length protein corresponding to Human ALDH1L1 aa 1 to the C-terminus. Immunogen expressed and purified from E. coli.
Database link: O75891 -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
Preservative: 0.03% Sodium azide -
Concentration information loading...
-
纯度
Whole antiserum -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab190298于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB | (1) |
1/5000 - 1/10000. Predicted molecular weight: 99 kDa.
|
ICC/IF |
1/2000.
|
说明 |
---|
WB
1/5000 - 1/10000. Predicted molecular weight: 99 kDa. |
ICC/IF
1/2000. |
靶标
-
组织特异性
Highly expressed in liver, pancreas and kidney. -
序列相似性
In the N-terminal section; belongs to the GART family.
In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
Contains 1 acyl carrier domain. -
细胞定位
Cytoplasm. - Information by UniProt
-
数据库链接
- Entrez Gene: 10840 Human
- Entrez Gene: 64392 Rat
- Omim: 600249 Human
- SwissProt: O75891 Human
- SwissProt: Q5RFM9 Orangutan
- SwissProt: P28037 Rat
- Unigene: 434435 Human
- Unigene: 2328 Rat
-
别名
- 10 formyltetrahydrofolate dehydrogenase antibody
- 10 FTHFDH antibody
- 10-formyltetrahydrofolate dehydrogenase antibody
see all
图片
-
Anti-ALDH1L1 antibody - Astrocyte Marker (ab190298) at 1/5000 dilution + Rat liver tissue homogenate
Predicted band size: 99 kDa
Observed band size: ~100 kDa why is the actual band size different from the predicted? -
Immunofluorescent analysis of human neuron-glial cell mixture cultures labeling ALDH1L1 with ab190298 at 1/2000 (red) and a monoclonal antibody against GFAP (green). Blue is a DNA stain. Astrocytes labeled by ab190298 and anti-GFAP appear yellow.
实验方案
数据表及文件
-
SDS download
-
Datasheet download
文献 (14)
ab190298 被引用在 14 文献中.
- Falcone C et al. Redefining varicose projection astrocytes in primates. Glia 70:145-154 (2022). PubMed: 34533866
- Badia-Soteras A et al. High-Throughput Analysis of Astrocyte Cultures Shows Prevention of Reactive Astrogliosis by the Multi-Nutrient Combination Fortasyn Connect. Cells 11:N/A (2022). PubMed: 35563732
- Bassil R et al. Improved modeling of human AD with an automated culturing platform for iPSC neurons, astrocytes and microglia. Nat Commun 12:5220 (2021). PubMed: 34471104
- Padmashri R et al. Modeling human-specific interlaminar astrocytes in the mouse cerebral cortex. J Comp Neurol 529:802-810 (2021). PubMed: 32639590
- Etienne J et al. Aldehyde dehydrogenases contribute to skeletal muscle homeostasis in healthy, aging, and Duchenne muscular dystrophy patients. J Cachexia Sarcopenia Muscle 11:1047-1069 (2020). PubMed: 32157826