重组Anti-ADCY9/AC9抗体[EPR16188] (ab191423)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR16188] to ADCY9/AC9
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
Related conjugates and formulations
概述
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产品名称
Anti-ADCY9/AC9抗体[EPR16188]
参阅全部 ADCY9/AC9 一抗 -
描述
兔单克隆抗体[EPR16188] to ADCY9/AC9 -
宿主
Rabbit -
经测试应用
适用于: WBmore details
不适用于: IHC-P -
种属反应性
与反应: Mouse, Rat, Human -
免疫原
Recombinant fragment. This information is proprietary to Abcam and/or its suppliers.
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阳性对照
- A549, K562, Mouse heart, Mouse spleen, Rat brain, PC12 and NIH 3T3 lysates.
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常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol, 0.05% BSA -
Concentration information loading...
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纯度
Protein A purified -
克隆
单克隆 -
克隆编号
EPR16188 -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab191423于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB | (2) |
1/1000 - 1/10000. Detects a band of approximately 151 kDa (predicted molecular weight: 151 kDa).
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说明 |
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WB
1/1000 - 1/10000. Detects a band of approximately 151 kDa (predicted molecular weight: 151 kDa). |
靶标
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功能
May play a fundamental role in situations where fine interplay between intracellular calcium and cAMP determines the cellular function. May be a physiologically relevant docking site for calcineurin. -
组织特异性
Expressed in multiple cells of the lung, with expression highest in airway smooth muscle. -
序列相似性
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Contains 2 guanylate cyclase domains. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 115 Human
- Entrez Gene: 11515 Mouse
- Entrez Gene: 302950 Rat
- Omim: 603302 Human
- SwissProt: O60503 Human
- SwissProt: P51830 Mouse
- Unigene: 391860 Human
- Unigene: 610484 Human
see all -
别名
- ADCY 9 antibody
- ADCY9 antibody
- ADCY9_HUMAN antibody
see all
图片
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All lanes : Anti-ADCY9/AC9 antibody [EPR16188] (ab191423) at 1/10000 dilution
Lane 1 : A549 lysate
Lane 2 : K562 lysate
Lysates/proteins at 20 µg per lane.
Secondary
All lanes : Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution
Predicted band size: 151 kDa -
All lanes : Anti-ADCY9/AC9 antibody [EPR16188] (ab191423) at 1/2000 dilution
Lane 1 : Mouse heart lysate
Lane 2 : Mouse spleen lysate
Lane 3 : Rat brain lysate
Lane 4 : PC12 lysate
Lane 5 : NIH 3T3 lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution
Predicted band size: 151 kDa
数据表及文件
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SDS download
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Datasheet download
Certificate of Compliance
文献 (9)
ab191423 被引用在 9 文献中.
- Liu J et al. miR-143-null Is against Diet-Induced Obesity by Promoting BAT Thermogenesis and Inhibiting WAT Adipogenesis. Int J Mol Sci 23:N/A (2022). PubMed: 36361843
- Liu J et al. LPS-Induced Inhibition of miR-143 Expression in Brown Adipocytes Promotes Thermogenesis and Fever. Int J Mol Sci 23:N/A (2022). PubMed: 36430282
- Li X et al. miR-142-3p targets AC9 to regulate sciatic nerve injury-induced neuropathic pain by regulating the cAMP/AMPK signalling pathway. Int J Mol Med 47:561-572 (2021). PubMed: 33416140
- Zhang X et al. Endogenous glutamate determines ferroptosis sensitivity via ADCY10-dependent YAP suppression in lung adenocarcinoma. Theranostics 11:5650-5674 (2021). PubMed: 33897873
- Hampson E et al. P-Rex1 Controls Sphingosine 1-Phosphate Receptor Signalling, Morphology, and Cell-Cycle Progression in Neuronal Cells. Cells 10:N/A (2021). PubMed: 34572121
- Cortes-Troncoso J et al. T cell exosome-derived miR-142-3p impairs glandular cell function in Sjögren's syndrome. JCI Insight 5:N/A (2020). PubMed: 32376798
- Simard M et al. A Tissue-Engineered Human Psoriatic Skin Model to Investigate the Implication of cAMP in Psoriasis: Differential Impacts of Cholera Toxin and Isoproterenol on cAMP Levels of the Epidermis. Int J Mol Sci 21:N/A (2020). PubMed: 32717879
- Wang T et al. Sorafenib promotes sensory conduction function recovery via miR-142-3p/AC9/cAMP axis post dorsal column injury. Neuropharmacology 148:347-357 (2019). PubMed: 30710569
- Tan X et al. The epithelial-to-mesenchymal transition activator ZEB1 initiates a prometastatic competing endogenous RNA network. J Clin Invest 128:1267-1282 (2018). PubMed: 29324442