Anti-ACOT1抗体(ab100915)
Key features and details
- Rabbit polyclonal to ACOT1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-ACOT1抗体 -
描述
兔多克隆抗体to ACOT1 -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse
-
免疫原
Recombinant fragment, corresponding to amino acids 183-421 of Human ACOT1 (BC132889).
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Lyophilized:Reconstitute in 200µl sterile water -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
Preservative: 0.02% Sodium azide -
Concentration information loading... -
纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab100915于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB | (1) |
1/1000 - 1/2000. Predicted molecular weight: 46 kDa.
|
| IHC-P |
1/100 - 1/500.
|
| 说明 |
|---|
|
WB
1/1000 - 1/2000. Predicted molecular weight: 46 kDa. |
|
IHC-P
1/100 - 1/500. |
靶标
-
相关性
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active towards fatty acyl-CoA with chain-lengths of C12-C16. -
细胞定位
Cytoplasmic -
数据库链接
- Entrez Gene: 641371 Human
- Entrez Gene: 26897 Mouse
- Omim: 614313 Human
- SwissProt: Q86TX2 Human
- SwissProt: O55137 Mouse
-
别名
- ACH2 antibody
- Acyl CoA thioesterase 1, cytosolic antibody
- Acyl coenzyme A thioesterase 1 antibody
see all
图片
-
Western blot - Anti-ACOT1 antibody (ab100915)All lanes : Anti-ACOT1 antibody (ab100915) at 1/1000 dilution
Lane 1 : Human Fetal Skin Lysate
Lane 2 : Human Fetal Liver Lysate
Lane 3 : Human Fetal Heart Lysate
Predicted band size: 46 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ACOT1 antibody (ab100915)ab100915, at 1/100 dilution, staining cytoplasmic ACOT1 in formalin-fixed, paraffin-embedded Human fetal thymus tissue, by Immunohistochemistry.
数据表及文件
-
SDS download
-
Datasheet download
文献 (3)
ab100915 被引用在 3 文献中.
- Liu Y et al. Acyl-CoA thioesterase 1 prevents cardiomyocytes from Doxorubicin-induced ferroptosis via shaping the lipid composition. Cell Death Dis 11:756 (2020). PubMed: 32934217
- Simsek D et al. The Mammalian Ribo-interactome Reveals Ribosome Functional Diversity and Heterogeneity. Cell 169:1051-1065.e18 (2017). PubMed: 28575669
- Jeckel KM et al. Dietary fatty acids alter left ventricular myocardial gene expression in Wistar rats. Nutr Res 34:694-706 (2014). WB ; Rat . PubMed: 25172377