Anti-ABCB6/PRP抗体- C-terminal (ab194409)
Key features and details
- Mouse polyclonal to ABCB6/PRP - C-terminal
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
概述
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产品名称
Anti-ABCB6/PRP抗体- C-terminal
参阅全部 ABCB6/PRP 一抗 -
描述
小鼠多克隆抗体to ABCB6/PRP - C-terminal -
宿主
Mouse -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Mouse, Rat, Human -
免疫原
Recombinant fragment (GST-tag) corresponding to Human ABCB6/PRP aa 700 to the C-terminus (C terminal). NP_005680
Database link: Q9NP58 -
阳性对照
- HeLa, RAW264.7, PC-12 and NIH3T3 cell lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
Constituent: 50% Glycerol (glycerin, glycerine) -
Concentration information loading...
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纯度
Whole antiserum -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab194409于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500 - 1/2500. Predicted molecular weight: 94 kDa.
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说明 |
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WB
1/500 - 1/2500. Predicted molecular weight: 94 kDa. |
靶标
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功能
Binds heme and porphyrins and functions in their ATP-dependent uptake into the mitochondria. Plays a crucial role in heme synthesis. -
组织特异性
Widely expressed. Highest expression in heart and skeletal muscles. -
序列相似性
Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
Contains 1 ABC transmembrane type-1 domain.
Contains 1 ABC transporter domain. -
发展阶段
Highly expressed in fetal liver. -
细胞定位
Mitochondrion outer membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 10058 Human
- Entrez Gene: 74104 Mouse
- Entrez Gene: 140669 Rat
- Omim: 605452 Human
- SwissProt: Q9NP58 Human
- SwissProt: Q9DC29 Mouse
- SwissProt: O70595 Rat
- Unigene: 107911 Human
see all -
别名
- ABC antibody
- ABC transporter umat antibody
- ABC14 antibody
see all
图片
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Anti-ABCB6/PRP antibody - C-terminal (ab194409) at 1/500 dilution + NIH3T3 cell lysate at 50 µg
Secondary
Goat Anti-Mouse IgG at 1/2500 dilution
Predicted band size: 94 kDa -
Anti-ABCB6/PRP antibody - C-terminal (ab194409) at 1/500 dilution + RAW264.7 cell lysate at 50 µg
Secondary
Goat Anti-Mouse IgG at 1/2500 dilution
Predicted band size: 94 kDa -
Anti-ABCB6/PRP antibody - C-terminal (ab194409) at 1/500 dilution + PC-12 cell lysate at 50 µg
Secondary
Goat Anti-Mouse IgG at 1/2500 dilution
Predicted band size: 94 kDa -
Anti-ABCB6/PRP antibody - C-terminal (ab194409) at 1/500 dilution + HeLa cell lysate at 50 µg
Secondary
Goat Anti-Mouse IgG at 1/2500 dilution
Predicted band size: 94 kDa
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab194409 被引用在 1 文献中.
- Morton AB et al. Mitochondrial accumulation of doxorubicin in cardiac and diaphragm muscle following exercise preconditioning. Mitochondrion N/A:N/A (2018). WB ; Rat . PubMed: 29474837