Anti-ABCA5抗体(ab99953)
Key features and details
- Rabbit polyclonal to ABCA5
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-ABCA5抗体 -
描述
兔多克隆抗体to ABCA5 -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat -
免疫原
Recombinant fragment corresponding to Human ABCA5 aa 1450 to the C-terminus. NM_018672
Database link: Q8WWZ7-1 -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Lyophilized:Reconstitute with 200ul distilled sterile water. Please note that if you receive this product in liquid form it has already been reconstituted as described and no further reconstitution is necessary. -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
Preservative: 0.02% Sodium azide
Constituent: 1% BSA -
Concentration information loading...
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纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab99953于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500 - 1/1000. Predicted molecular weight: 187 kDa.
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IHC-P |
1/100 - 1/500.
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说明 |
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WB
1/500 - 1/1000. Predicted molecular weight: 187 kDa. |
IHC-P
1/100 - 1/500. |
靶标
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功能
May play a role in the processing of autolysosomes. -
组织特异性
Ubiquitously expressed. Highly expressed in testis, skeletal muscle, kidney, liver and placenta. -
序列相似性
Belongs to the ABC transporter superfamily. ABCA family.
Contains 2 ABC transporter domains. -
发展阶段
Expressed in fetal liver, kidney and brain. -
翻译后修饰
N-glycosylated. -
细胞定位
Lysosome membrane. Late endosome membrane. Golgi apparatus membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 23461 Human
- Entrez Gene: 217265 Mouse
- Entrez Gene: 286970 Rat
- Omim: 612503 Human
- SwissProt: Q8WWZ7 Human
- SwissProt: Q8K448 Mouse
- SwissProt: Q8CF82 Rat
- Unigene: 421474 Human
see all -
别名
- ABC13 antibody
- ABCA5 antibody
- ABCA5_HUMAN antibody
see all
图片
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab99953 被引用在 2 文献中.
- Palmer MA et al. Localisation and regulation of cholesterol transporters in the human hair follicle: mapping changes across the hair cycle. Histochem Cell Biol 155:529-545 (2021). PubMed: 33404706
- DeStefano GM et al. Mutations in the Cholesterol Transporter Gene ABCA5 Are Associated with Excessive Hair Overgrowth. PLoS Genet 10:e1004333 (2014). WB, IHC-P, ICC/IF ; Human . PubMed: 24831815