Anti-AANAT抗体(ab3506)

Anti-AANAT抗体
参阅全部 AANAT 一抗

兔多克隆抗体to AANAT

Rabbit

与反应: Rat
预测可用于: Mouse, Hamster, Human, Chimpanzee, Rhesus monkey

Synthetic peptide corresponding to Rat AANAT aa 195-205 (C terminal).
Sequence:

CHTFLRRNSGC

(Peptide available as ab5004)

Run BLAST with Run BLAST with

Liquid

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 99% PBS

Immunogen affinity purified

Total anti-C-terminal AA-NAT-specific IgG was affinity purified on resin-coupled non-phosphopeptide. Phospho-specific carboxy-terminal IgG was subsequently isolated on resin-coupled phosphopeptide.

Pineal gland serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AA-NAT) is an ~23 kDa protein which is the rate-limiting enzyme in melatonin synthesis. Melatonin serves as the hormonal signal of the daily light/dark cycle, or body clock. The nocturnal oscillation in enzyme activity ranges by 10- to 100-fold depending on species among vertebrates. Studies have shown that AA-NAT is regulated by cAMP at both the mRNA and protein levels. AA-NAT has putative protein kinase A (PKA) sites at Thr29 and Ser206. Phosphorylation of AA-NAT at these residues might play a role in protein inactivation via proteasome-dependent degradation.

多克隆

IgG

• Neuroscience
• Neurotransmitter
• Biogenic Amines
• Serotonin / 5HT

• Neuroscience
• Neurology process
• Circadian Rhythm
• Hormones

• Cancer
• Cancer Metabolism
• Metabolic signaling pathway
• Hormone biosynthesis

• Metabolism
• Pathways and Processes
• Endocrine metabolism
• Hormone biosynthesis

• Metabolism
• Types of disease
• Cancer

• Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
• Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

• AANAT peptide (ab5004)

• Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)

• Recombinant Human AANAT protein (Tagged) (ab239443)