Anti-SCGF beta抗体(ab9835)
Key features and details
- Goat polyclonal to SCGF beta
- Suitable for: Sandwich ELISA, Neutralising, WB, ELISA
- Reacts with: Human
- Isotype: unknown
概述
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产品名称
Anti-SCGF beta抗体
参阅全部 SCGF beta 一抗 -
描述
山羊多克隆抗体to SCGF beta -
宿主
Goat -
经测试应用
适用于: Sandwich ELISA, Neutralising, WB, ELISAmore details -
种属反应性
与反应: Human -
免疫原
Recombinant full length protein corresponding to Human SCGF beta aa 1-350.
Database link: Q9Y240 -
阳性对照
- Recombinant human SCGF beta protein (ab9836) can be used as a positive control in WB.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Lyophilized:Reconstitute with 200µl of sterile water. -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
存储溶液
pH: 7.40
No preservative, sterile filtered -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
unknown -
轻链类型
unknown -
研究领域
相关产品
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Compatible Secondaries
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Positive Controls
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Recombinant Protein
应用
应用 | Ab评论 | 说明 |
---|---|---|
Sandwich ELISA |
Use at an assay dependent concentration.
To detect Human SCGF-beta by sandwich ELISA (using 100 ul/well antibody solution) a concentration of 0.5 - 2.0 ug/ml of this antibody is required. |
|
Neutralising |
Use at an assay dependent concentration.
for one-half maximal inhibition [ND50] of the biological activity of hSCGFb (30.00 ng/ml). |
|
WB |
Use at an assay dependent concentration.
|
|
ELISA |
Use at an assay dependent concentration.
Allows the detection of 0.2 - 0.4 ng/well of recombinant hSCGFb. |
说明 |
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Sandwich ELISA
Use at an assay dependent concentration. To detect Human SCGF-beta by sandwich ELISA (using 100 ul/well antibody solution) a concentration of 0.5 - 2.0 ug/ml of this antibody is required. |
Neutralising
Use at an assay dependent concentration. for one-half maximal inhibition [ND50] of the biological activity of hSCGFb (30.00 ng/ml). |
WB
Use at an assay dependent concentration. |
ELISA
Use at an assay dependent concentration. Allows the detection of 0.2 - 0.4 ng/well of recombinant hSCGFb. |
靶标
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功能
Stimulates the proliferation and differentiation of hematopoietic precursor cells from various lineages, including erythrocytes, lymphocytes, granulocytes and macrophages. Acts synergistically with other cytokines, including IL-3, GCSF, GMCSF and FLT3 ligand. Suppresses SCF-stimulated erythrocyte proliferation. -
组织特异性
Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver. -
序列相似性
Contains 1 C-type lectin domain. -
发展阶段
In the bone marrow, expression is limited to immature neutrophils. Expression was not detected in circulating mature neutrophils. -
翻译后修饰
O-glycosylated. Probably sulfated on the O-glycans. -
细胞定位
Cytoplasm. Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 6320 Human
- Omim: 604713 Human
- SwissProt: Q9Y240 Human
- Unigene: 512680 Human
- Unigene: 727919 Human
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别名
- C type lectin domain family 11 member A antibody
- C type lectin superfamily member 3 antibody
- C-type lectin domain family 11 member A antibody
see all
数据表及文件
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Datasheet download
文献 (1)
ab9835 被引用在 1 文献中.
- Hiraoka A Leukemia cell lines require self-secreted stem cell growth factor (SCGF) for their proliferation. Leuk Res 32:1623-5 (2008). Human . PubMed: 18289675