重组人Cornulin蛋白(ab93883)
Key features and details
- Expression system: Escherichia coli
- Purity: > 85% SDS-PAGE
- Suitable for: SDS-PAGE
描述
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产品名称
重组人Cornulin蛋白 -
纯度
> 85 % SDS-PAGE.
Purified using conventional chromatography techniques -
表达系统
Escherichia coli -
蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
氨基酸
1 to 495
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相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab93883 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
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形式
Liquid -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
pH: 7.40
Constituents: 10% Glycerol (glycerin, glycerine), PBS
常规信息
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别名
- 53 kDa putative calcium binding protein
- 53 kDa putative calcium-binding protein
- 53 kDa squamous epithelial induced stress protein
see all -
功能
Survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines, attenuates deoxycholic acid (DCA)-induced apoptotic cell death and release of calcium. When overexpressed in oral squamous carcinom cell lines, regulates negatively cell proliferation by the induction of G1 arrest. -
组织特异性
Squamous epithelia cell-specific. Expressed in the esophagus (periphery of the cells of the granular and the upper spinous layers), foreskin (granular and lower cornified cells), scalp skin (granular layer), inner root sheath of the hair follicle and in primary keratinocytes (at protein level). Expressed in the squamous epithelium of the cervix, esophagus, foreskin and larynx. Expressed in the fetal bladder and scalp skin. Expressed at very low levels in the lung, kidney, uterus, skeletal muscle, heart and fetal brain. Undetectable or barely detectable in esophageal and oral squamous cell carcinoma compared with the matched adjacent normal esophageal mucosa. Undetectable or barely detectable in larynx and esophagus from patients with pH-documented laryngopharyngeal reflux (LPR). -
序列相似性
Belongs to the S100-fused protein family.
Contains 1 EF-hand domain. -
结构域
The EF-hand is necessary for the colony survival activity to protect cells from death induced by exposure to DCA. -
细胞定位
Cytoplasm. Does not colocalize with TGM1. - Information by UniProt
图片
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab93883 尚未被引用在任何文献中。