重组食蟹猴IL-4 Receptor alpha蛋白(Fc Chimera) (ab208322)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 95% SDS-PAGE
- Endotoxin level: < 1.000 Eu/µg
- Suitable for: SDS-PAGE
描述
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产品名称
重组食蟹猴IL-4 Receptor alpha蛋白(Fc Chimera)
参阅全部 IL-4 Receptor alpha 蛋白酶 -
纯度
> 95 % SDS-PAGE. -
内毒素水平
< 1.000 Eu/µg -
表达系统
HEK 293 cells -
Accession
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蛋白长度
Protein fragment -
无动物成分
No -
性质
Recombinant -
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种属
Cynomolgus monkey -
序列
MKVLQ EPACVSDYMS ISTCEWKMGG PTNCSAELRL LYQLVFQSSE THTCVPENNG GVGCVCHLLM DDVVSMDNYT LDLWAGQQLL WKGSFKPSEH VKPRAPGNLT VHTNVSDTVL LTWSNPYPPD NYLYNDLTYA VNIWSENDPA YSRIHNVTYL KPTLRIPAST LKSGISYRAR VRAWAQHYNT TWSEWSPSTK WYNSYREPFE QR -
预测分子量
50 kDa including tags -
氨基酸
26 to 232 -
额外的序列信息
Fused with a Human IgG1 Fc tag at the C-terminus.
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技术指标
Our Abpromise guarantee covers the use of ab208322 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
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形式
Lyophilized -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Store at -80°C.
pH: 7.4
Constituents: 0.61% Tris, 0.75% Glycine
Note: 5-10% trehalose is commonly used for freeze drying, and after reconstitution, the trehalose is mostly about 3-5%. -
复溶Reconstitute with sterile deionized water to a concentration of 200 µg/ml.
常规信息
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别名
- IL4 binding protein
- IL4 BP
- IL4 Receptor alpha
see all -
相关性
IL-4 Receptor alpha (IL-4RA) is the alpha chain of the interleukin 4 receptor which binds to both interleukin 4 and interleukin 13 to regulate IgE production, chemokine and mucus production at sites of allergic inflammmation. The IL4 response is involved in promoting Th2 differentiation. The secreted extracellular domain of IL-4R alpha, called sIL4R alpha, can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. It has no signaling abilities. Allelic variations in the IL-4RA gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. -
细胞定位
Cell membrane; single-pass type I membrane protein. Isoform 2: Secreted protein.
图片
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Immobilized Human IL-4, Tag Free (ab155733) at 5 μg/mL (100 μL/well) can bind Cynomolgus / Rhesus macaque IL-4 R alpha, Fc Tag (ab208322) with a linear range of 10-78 ng/mL
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SDS-PAGE analysis of reduced ab208322 stained overnight with Coomassie Blue..
Note: The reducing protein migrates as 60-90 kDa in SDS-PAGE.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab208322 尚未被引用在任何文献中。