参阅全部 PKN2 一抗
描述兔单克隆抗体[E352] to PKN2
经测试应用适用于: WB, IHC-P, ICC, Flow Cyt, IPmore details
种属反应性与反应: Mouse, Rat, Human
Synthetic peptide within Human PKN2 aa 1-100 (N terminal). The exact sequence is proprietary.
- 293T cell lysate human colon carcinoma
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents
This product is a recombinant rabbit monoclonal antibody.
存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 40% Glycerol, 9.85% Tris glycine, 50% Tissue culture supernatant
纯度Tissue culture supernatant
Our Abpromise guarantee covers the use of ab32395 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Detects a band of approximately 112 kDa (predicted molecular weight: 112 kDa).|
|IHC-P||Use at an assay dependent concentration.|
|ICC||1/250 - 1/500.|
ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
功能Exhibits a preference for highly basic protein substrates.
序列相似性Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
Contains 1 AGC-kinase C-terminal domain.
Contains 1 C2 domain.
Contains 1 protein kinase domain.
Contains 3 REM (Hr1) repeats.
结构域The C1 domain does not bind the diacylglycerol (DAG).
Activated by limited proteolysis with trypsin.
- Information by UniProt
- Cardiolipin activated protein kinase Pak2 antibody
- MGC150606 antibody
- MGC71074 antibody
This product has been referenced in:
- Mather Q et al. A novel protein expression signature differentiates benign lipomas from well-differentiated liposarcomas. Mol Clin Oncol 7:315-321 (2017). Read more (PubMed: 28781809) »
- Yang CS et al. The protein kinase C super-family member PKN is regulated by mTOR and influences differentiation during prostate cancer progression. Prostate 77:1452-1467 (2017). Read more (PubMed: 28875501) »