存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
存储溶液Preservative: 0.05% Sodium azide
Constituent: Whole serum
Our Abpromise guarantee covers the use of ab10266 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000. Predicted molecular weight: 47,8 kDa.|
|IHC-FoFr||Use at an assay dependent concentration.|
|IHC-P||Use at an assay dependent concentration. PubMed: 21969132|
功能Ion channel gated by extracellular ATP involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling. Mediates synaptic transmission between neurons and from neurons to smooth muscle.
疾病相关Deafness, autosomal dominant, 41
序列相似性Belongs to the P2X receptor family.
细胞定位Cell membrane. Localizes to the apical membranes of hair cells in the organ of Corti.
- Information by UniProt
形式There are 7 isoforms produced by alternative splicing.
- ATP receptor antibody
- MGC129601 antibody
- P2RX 2 antibody
This product has been referenced in:
- Kútna V et al. Enigmatic cerebrospinal fluid-contacting neurons arise even after the termination of neurogenesis in the rat spinal cord during embryonic development and retain their immature-like characteristics until adulthood. Acta Histochem N/A:N/A (2013). Read more (PubMed: 24063862) »
- Wu T et al. Functional expression of P2X4 receptor in capillary endothelial cells of the cochlear spiral ligament and its role in regulating the capillary diameter. Am J Physiol Heart Circ Physiol 301:H69-78 (2011). Read more (PubMed: 21460192) »