Kynurenic acid sodium salt,Endogenous ionotropic / nicotinic拮抗剂(ab120256)
Key features and details
- Endogenous ionotropic / nicotinic antagonist; water soluble
- CAS Number: 2439-02-3
Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
Kynurenic acid sodium salt,Endogenous ionotropic / nicotinic拮抗剂 -
描述
Endogenous ionotropic / nicotinic拮抗剂; water soluble -
生物学描述
Endogenous antagonist at ionotropic, glycine and α7 nicotinic receptors. Neuroprotective in vivo. Water soluble form.
Also available in simple stock solutions (ab146693) - add 1 ml of water to get an exact, ready-to-use concentration. -
CAS编号
2439-02-3 -
化学结构
性能
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化学名称
4-Hydroxyquinoline-2-carboxylic acid sodium salt
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分子量
211.15 -
分子式
C10H6NNaO3 -
PubChem识别号
52974250 -
存放说明
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in water to 100 mM
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处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C(O[Na])c1cc(O)c2ccccc2n1 -
来源
Synthetic
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研究领域
相关产品
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图片
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (14)
ab120256 被引用在 14 文献中.
- Liu M et al. Make war not love: The neural substrate underlying a state-dependent switch in female social behavior. Neuron 110:841-856.e6 (2022). PubMed: 34982958
- Merlaud Z et al. Conformational state-dependent regulation of GABAA receptor diffusion and subsynaptic domains. iScience 25:105467 (2022). PubMed: 36388998
- McElvain LE et al. Specific populations of basal ganglia output neurons target distinct brain stem areas while collateralizing throughout the diencephalon. Neuron 109:1721-1738.e4 (2021). PubMed: 33823137
- Yu W et al. Periaqueductal gray/dorsal raphe dopamine neurons contribute to sex differences in pain-related behaviors. Neuron 109:1365-1380.e5 (2021). PubMed: 33740416
- Vaden JH et al. The readily-releasable pool dynamically regulates multivesicular release. Elife 8:N/A (2019). PubMed: 31364987