抗乙型肝炎病毒Surface Antigen (Ad/Ay)抗体(ab9193)
Key features and details
- Horse polyclonal to Hepatitis B Virus Surface Antigen (Ad/Ay)
- Suitable for: ELISA
- Reacts with: Hepatitis B virus
- Isotype: IgG
概述
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产品名称
抗乙型肝炎病毒Surface Antigen (Ad/Ay)抗体
参阅全部 Hepatitis B Virus Surface Antigen (Ad/Ay) 一抗 -
描述
马多克隆抗体to乙型肝炎病毒Surface Antigen (Ad/Ay) -
宿主
Horse -
特异性
This antibody is specific for Hepatitis B surface antigen -
经测试应用
适用于: ELISAmore details -
种属反应性
与反应: Hepatitis B virus -
免疫原
Immunization of horses with highly purified Ad/Ay antigen.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.20
Constituents: 0.0268% PBS, 0.87% Sodium chloride -
Concentration information loading...
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纯度
Affinity purified -
纯化说明
This antibody was immunoaffinity purified from non-recombinant hepatitis antigens. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Conjugation kits
应用
应用 | Ab评论 | 说明 |
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ELISA |
Use at an assay dependent concentration.
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说明 |
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ELISA
Use at an assay dependent concentration. |
靶标
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相关性
Hepatitis B Virus (HBV) infection induces a disease state characterised by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but as the disease progresses this antigen may no longer be present in the blood and tests for HBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronic hepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr. -
细胞定位
Virion membrane -
数据库链接
- Entrez Gene: 2828293 Hepatitis B virus
- Entrez Gene: 944569 Hepatitis B virus
- SwissProt: P03138 Hepatitis B virus
- SwissProt: P03140 Hepatitis B virus
- SwissProt: P03141 Hepatitis B virus
- SwissProt: Q81157 Hepatitis B virus
- SwissProt: Q81158 Hepatitis B virus
- SwissProt: Q81159 Hepatitis B virus
see all -
别名
- HBsAg antibody
- HBV major surface antigen antibody
- HBV surface antigen antibody
see all
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (28)
ab9193 被引用在 28 文献中.
- Zhang J et al. Interleukin-17A pretreatment attenuates the anti-hepatitis B virus efficacy of interferon-alpha by reducing activation of the interferon-stimulated gene factor 3 transcriptional complex in hepatitis B virus-expressing HepG2 cells. Virol J 19:28 (2022). PubMed: 35144643
- Liu T et al. In vitro investigation of HBV clinical isolates from Chinese patients reveals that genotype C isolates possess higher infectivity than genotype B isolates. Virol Sin 37:398-407 (2022). PubMed: 35314401
- Pantazica AM et al. Efficient cellular and humoral immune response and production of virus-neutralizing antibodies by the Hepatitis B Virus S/preS116-42 antigen. Front Immunol 13:941243 (2022). PubMed: 35935966
- Zhang J et al. ATP1B3 Restricts Hepatitis B Virus Replication Via Reducing the Expression of the Envelope Proteins. Virol Sin N/A:N/A (2021). PubMed: 33534085
- Dou Y et al. The CAG promoter maintains high-level transgene expression in HEK293 cells. FEBS Open Bio 11:95-104 (2021). PubMed: 33155423