产品名称Anti-DR1抗体- Azide free
参阅全部 DR1 一抗
描述鸡多克隆抗体to DR1 - Azide free
特异性This antibody is specific for Hypothetical protein DKFZp666G145.
经测试应用适用于: WBmore details
种属反应性与反应: Mouse, Human
Full length protein, corresponding to amino acids 1-176 of Hypothetical protein DKFZp666G145.
- Hela cells and 293 cell line.
存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Concentration information loading...
纯度Immunogen affinity purified
- Epigenetics and Nuclear Signaling
- Polymerase associated factors
- Pol II Transcription
Our Abpromise guarantee covers the use of ab37663 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/2000. Detects a band of approximately 22 kDa (predicted molecular weight: 19 kDa).|
功能The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
序列相似性Belongs to the NC2 beta/DR1 family.
Contains 1 histone-fold domain.
翻译后修饰Phosphorylation regulates its interaction with TBP. Not phosphorylated when bound to DRAP1.
- Information by UniProt
- Down regulator of transcription 1 antibody
- Down regulator of transcription 1 TBP binding antibody
- Down-regulator of transcription 1 antibody
Lane 1 : Anti-DR1 antibody - Azide free (ab37663) at 1/2000 dilution
Lanes 2-3 : Anti-DR1 antibody - Azide free (ab37663) at 1/500 dilution
Lane 1 : E coli-derived fusion protein
Lane 2 : 293 cell line.
Lane 3 : Hela cells line.
All lanes : Goat anti-IgY-HRP. at 1/1000 dilution
Predicted band size: 19 kDa
Observed band size: 22 kDa why is the actual band size different from the predicted?
Top bands (~75kDa) are fusion proteins.
ab37663 has not yet been referenced specifically in any publications.