PE Anti-CD40抗体[1C10] (ab25270)
Key features and details
- PE Rat monoclonal [1C10] to CD40
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG2a
Related conjugates and formulations
概述
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产品名称
PE Anti-CD40抗体[1C10]
参阅全部 CD40 一抗 -
描述
PE大鼠单克隆抗体[1C10] to CD40 -
宿主
Rat -
偶联物
PE. Ex: 488nm, Em: 575nm -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Mouse -
免疫原
Recombinant fragment corresponding to CD40. sCD40
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. Store In the Dark. -
存储溶液
pH: 7.3
Preservative: 0.09% Sodium azide
Constituents: PBS, Sucrose
Stabilising agent. -
Concentration information loading...
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纯度
Affinity purified -
克隆
单克隆 -
克隆编号
1C10 -
同种型
IgG2a -
轻链类型
kappa -
研究领域
相关产品
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Alternative Versions
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab25270于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
Flow Cyt |
Use at an assay dependent concentration.
ab134674 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
说明 |
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Flow Cyt
Use at an assay dependent concentration. ab134674 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
靶标
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功能
Receptor for TNFSF5/CD40LG. -
组织特异性
B-cells and in primary carcinomas. -
疾病相关
Defects in CD40 are the cause of hyper-IgM immunodeficiency syndrome type 3 (HIGM3) [MIM:606843]; also known as hyper-IgM syndrome 3. HIGM3 is an autosomal recessive disorder which includes an inability of B cells to undergo isotype switching, one of the final differentiation steps in the humoral immune system, an inability to mount an antibody-specific immune response, and a lack of germinal center formation. -
序列相似性
Contains 4 TNFR-Cys repeats. -
细胞定位
Secreted and Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 21939 Mouse
- SwissProt: P27512 Mouse
- Unigene: 271833 Mouse
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别名
- AI326936 antibody
- B cell associated molecule CD40 antibody
- B cell surface antigen CD40 antibody
see all
图片
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Flow Cytometry analysis of BALB/c mouse splenocytes stained with Anti-CD40 antibody [1C10] (Phycoerythrin) (ab25270) (0.1 μg/106 cells) and Anti-CD3 antibody [C363.29B] (FITC) (ab24948).
数据表及文件
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Datasheet download
文献 (0)
ab25270 尚未被引用在任何文献中。