Boc-D-FMK,caspase抑制剂(ab142036)
Key features and details
- Irreversible general caspase inhibitor. Cell-permeable.
- CAS Number: 187389-53-3
- Soluble in DMSO to 20 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
Boc-D-FMK,caspase抑制剂 -
描述
Irreversible general caspase抑制剂. Cell-permeable. -
生物学描述
Irreversible general caspase inhibitor. Blocks hepatocyte apoptosis in vivo. Active in vitro and in vivo. Cell-permeable.
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CAS编号
187389-53-3 -
化学结构
性能
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化学名称
Boc-Asp(OMe)-fluoromethyl ketone -
分子量
263.26 -
分子式
C11H18FNO5 -
PubChem识别号
16760348 -
存放说明
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in DMSO to 20 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(C)(C)OC(=O)NC(CC(=O)OC)C(=O)CF -
来源
Synthetic
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研究领域
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (2)
ab142036 被引用在 2 文献中.
- de León A et al. NGF-Dependent and BDNF-Dependent DRG Sensory Neurons Deploy Distinct Degenerative Signaling Mechanisms. eNeuro 8:N/A (2021). PubMed: 33372032
- Qiu X et al. CD40 ligand induces RIP1-dependent, necroptosis-like cell death in low-grade serous but not serous borderline ovarian tumor cells. Cell Death Dis 6:e1864 (2015). PubMed: 26313915