概述

  • 产品名称Anti-ZRANB1抗体
    参阅全部 ZRANB1 一抗
  • 描述
    兔多克隆抗体to ZRANB1
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 672-701 of Human ZRANB1

  • 阳性对照
    • K562 cell lysate. Mouse brain tissue.

性能

应用

Our Abpromise guarantee covers the use of ab103417 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 81 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Positive regulator of the Wnt signaling pathway that specifically cleaves 'Lys-63'-linked ubiquitin chains. Acts by deubiquitinating APC protein, a negative regulator of Wnt-mediated transcription. May also modulate TNF-alpha signaling.
  • 组织特异性Widely expressed.
  • 序列相似性Belongs to the peptidase C64 family.
    Contains 1 OTU domain.
    Contains 3 RanBP2-type zinc fingers.
  • 结构域The OTU domain mediates the deubiquitinating activity.
    The RanBP2-type zinc fingers mediate the specific interaction with 'Lys-63'-linked ubiquitin.
  • 细胞定位Cytoplasm. Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DKFZp762P2216 antibody
    • hTrabid antibody
    • Trabid antibody
    • TRAF-binding protein domain antibody
    • Ubiquitin thioesterase ZRANB1 antibody
    • Zinc finger Ran-binding domain-containing protein 1 antibody
    • ZRAN1_HUMAN antibody
    • ZRANB1 antibody
    see all

Anti-ZRANB1 antibody 图像

  • Anti-ZRANB1 antibody (ab103417) at 1/100 dilution + K562 cell lysate at 35 µg

    Predicted band size : 81 kDa
  • ab103417, at 1/50 dilution, staining ZRANB1 by immunohistochemistry in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
  • Anti-ZRANB1 antibody (ab103417) at 1/100 dilution + Mouse cerebellum tissue lysate at 35 µg

    Predicted band size : 81 kDa

Anti-ZRANB1 antibody (ab103417)参考文献

ab103417 has not yet been referenced specifically in any publications.

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