产品名称 Anti-ZRANB1抗体 参阅全部 ZRANB1 一抗
WB, IHC-P more details
Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 672-701 of Human ZRANB1
K562 cell lysate. Mouse brain tissue.
存放说明 Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
存储溶液 Preservative: 0.09% Sodium Azide
Concentration information loading...
纯度 Immunogen affinity purified
纯化说明 Purified through a protein A column, followed by peptide affinity purification.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Predicted molecular weight: 81 kDa.
1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
功能 Positive regulator of the Wnt signaling pathway that specifically cleaves 'Lys-63'-linked ubiquitin chains. Acts by deubiquitinating APC protein, a negative regulator of Wnt-mediated transcription. May also modulate TNF-alpha signaling.
组织特异性 Widely expressed.
序列相似性 Belongs to the peptidase C64 family. Contains 1 OTU domain. Contains 3 RanBP2-type zinc fingers.
结构域 The OTU domain mediates the deubiquitinating activity. The RanBP2-type zinc fingers mediate the specific interaction with 'Lys-63'-linked ubiquitin.
细胞定位 Cytoplasm. Nucleus.
Information by UniProt
Anti-ZRANB1 antibody 图像
Western blot - ZRANB1 antibody (ab103417)
Anti-ZRANB1 antibody (ab103417) at 1/100 dilution + K562 cell lysate at 35 µg Predicted band size : 81 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - ZRANB1 antibody (ab103417)
ab103417, at 1/50 dilution, staining ZRANB1 by immunohistochemistry in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot - Anti-ZRANB1 antibody (ab103417)
Anti-ZRANB1 antibody (ab103417) at 1/100 dilution + Mouse cerebellum tissue lysate at 35 µg Predicted band size : 81 kDa
Anti-ZRANB1 antibody (ab103417)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"