概述

  • 产品名称Anti-ZNRF1抗体
    参阅全部 ZNRF1 一抗
  • 描述
    兔多克隆抗体to ZNRF1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Guinea pig, Cow, Cat, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 2-51 (GGKQSTAARS RGPFPGVSTD DSAVPPPGGA PHFGHYRTGG GAMGLRSRSV) of Human ZNRF1 (NP_115644).

  • 阳性对照
    • Human fetal spleen lysate

性能

应用

Our Abpromise guarantee covers the use of ab94467 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 24 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to substrates. May play a role in the establisment and maintenance of neuronal transmission and plasticity via its ubiquitin-protein ligase activity.
  • 组织特异性Expressed primarily in the nervous system, with expression higher in developing brain relative to adult. Expressed at low levels in testis and thymus.
  • 通路Protein modification; protein ubiquitination.
  • 序列相似性Contains 1 RING-type zinc finger.
  • 结构域The RING-type zinc finger domain is required for E3 ligase activity.
  • 细胞定位Endosome. Lysosome. Membrane. Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Associated with synaptic vesicle membranes in neurons.
  • Information by UniProt
  • 数据库链接
  • 别名
    • B830022L21Rik antibody
    • DKFZp434E229 antibody
    • E3 ubiquitin protein ligase ZNRF1 antibody
    • E3 ubiquitin-protein ligase ZNRF1 antibody
    • EC 6.3.2.- antibody
    • FLJ14846 antibody
    • MGC101991 antibody
    • MGC15430 antibody
    • Nerve injury gene 283 antibody
    • Nerve injury induced gene 283 protein antibody
    • Nerve injury-induced gene 283 protein antibody
    • NIN283 antibody
    • Rnf42 antibody
    • Zinc and ring finger 1 antibody
    • zinc and ring finger protein 1 antibody
    • zinc finger and ring finger protein 1 antibody
    • Zinc/RING finger protein 1 antibody
    • ZNRF 1 antibody
    • znrf1 antibody
    • ZNRF1_HUMAN antibody
    • Zrfp1 antibody
    see all

Anti-ZNRF1 antibody 图像

  • Anti-ZNRF1 antibody (ab94467) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal spleen lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 24 kDa

Anti-ZNRF1 antibody (ab94467)参考文献

ab94467 has not yet been referenced specifically in any publications.

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