概述

  • 产品名称Anti-ZNRF1抗体
    参阅全部 ZNRF1 一抗
  • 描述
    小鼠单克隆抗体to ZNRF1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 74-179 of Human ZNRF1

性能

应用

Our Abpromise guarantee covers the use of ab57938 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to substrates. May play a role in the establisment and maintenance of neuronal transmission and plasticity via its ubiquitin-protein ligase activity.
    • 组织特异性Expressed primarily in the nervous system, with expression higher in developing brain relative to adult. Expressed at low levels in testis and thymus.
    • 通路Protein modification; protein ubiquitination.
    • 序列相似性Contains 1 RING-type zinc finger.
    • 结构域The RING-type zinc finger domain is required for E3 ligase activity.
    • 细胞定位Endosome. Lysosome. Membrane. Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Associated with synaptic vesicle membranes in neurons.
    • Information by UniProt
    • 数据库链接
    • 别名
      • B830022L21Rik antibody
      • DKFZp434E229 antibody
      • E3 ubiquitin protein ligase ZNRF1 antibody
      • E3 ubiquitin-protein ligase ZNRF1 antibody
      • EC 6.3.2.- antibody
      • FLJ14846 antibody
      • MGC101991 antibody
      • MGC15430 antibody
      • Nerve injury gene 283 antibody
      • Nerve injury induced gene 283 protein antibody
      • Nerve injury-induced gene 283 protein antibody
      • NIN283 antibody
      • Rnf42 antibody
      • Zinc and ring finger 1 antibody
      • zinc and ring finger protein 1 antibody
      • zinc finger and ring finger protein 1 antibody
      • Zinc/RING finger protein 1 antibody
      • ZNRF 1 antibody
      • znrf1 antibody
      • ZNRF1_HUMAN antibody
      • Zrfp1 antibody
      see all

    Anti-ZNRF1 antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab57938 ZNRF1 antibody at 1ug/ml. Predicted band size of immunogen is 38 kDa

    Anti-ZNRF1 antibody (ab57938)参考文献

    ab57938 has not yet been referenced specifically in any publications.

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