概述

  • 产品名称Anti-ZNF750抗体
    参阅全部 ZNF750 一抗
  • 描述
    兔多克隆抗体to ZNF750
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    antigen sequence, corresponding to amino acids 73-187 of Human ZNF750.

  • 阳性对照
    • Human stomach tissue.

性能

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应用

Our Abpromise guarantee covers the use of ab121730 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Perform Heat Induced Epitope Retrieval (HIER) at pH 6 using a pressure boiler as heat source.

靶标

  • 组织特异性Expressed in the skin, prostate, lung, placenta and thymus, and at low level in T-cells. Not expressed in peripheral blood leukocytes, pancreas and brain. Clearly expressed in primary keratinocytes but not in fibroblasts.
  • 疾病相关Defects in ZNF750 are the cause of Seborrhea-like dermatitis with psoriasiform (SLDP) [MIM:610227]. SLDP is characterized by a chronic fine diffuse scaly erythematous rash on the face, particularly on the chin, nasolabial folds and eyebrows, around earlobes and over the scalp. The rash exacerbate in the winter, with emotional stress and after strenuous physical activity. Hyperkeratosis of skin over the elbows, knees, palms, soles and metacarpophalangeal joints is evident. There is no arthralgia, arthritis or neurological disorders.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Protein ZNF750 antibody
    • ZFP750 antibody
    • Zinc finger protein 750 antibody
    • ZN750_HUMAN antibody
    • ZNF750 antibody
    see all

Anti-ZNF750 antibody 图像

  • ab121730 at 1/125 dilution staining ZNF750in Paraffin-embedded Human Stomach tissue by Immunohistochemistry. Note: strong cytoplasmic positivity in parietal cells.

Anti-ZNF750 antibody (ab121730)参考文献

ab121730 has not yet been referenced specifically in any publications.

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