概述

  • 产品名称Anti-ZNF750抗体
    参阅全部 ZNF750 一抗
  • 描述
    兔多克隆抗体to ZNF750
  • 经测试应用适用于: IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    antigen sequence, corresponding to C terminal amino acids 621-721 of Human ZNF750.

  • 阳性对照
    • Human vagina tissue.

性能

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应用

Our Abpromise guarantee covers the use of ab121685 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use a concentration of 1 - 4 µg/ml.

Recommend PFA Fixation and Triton X-100 treatment

靶标

  • 组织特异性Expressed in the skin, prostate, lung, placenta and thymus, and at low level in T-cells. Not expressed in peripheral blood leukocytes, pancreas and brain. Clearly expressed in primary keratinocytes but not in fibroblasts.
  • 疾病相关Defects in ZNF750 are the cause of Seborrhea-like dermatitis with psoriasiform (SLDP) [MIM:610227]. SLDP is characterized by a chronic fine diffuse scaly erythematous rash on the face, particularly on the chin, nasolabial folds and eyebrows, around earlobes and over the scalp. The rash exacerbate in the winter, with emotional stress and after strenuous physical activity. Hyperkeratosis of skin over the elbows, knees, palms, soles and metacarpophalangeal joints is evident. There is no arthralgia, arthritis or neurological disorders.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Protein ZNF750 antibody
    • ZFP750 antibody
    • Zinc finger protein 750 antibody
    • ZN750_HUMAN antibody
    • ZNF750 antibody
    see all

Anti-ZNF750 antibody 图像

  • Immunofluorescent staining of Human cell line U-251MG shows positivity in nucleus and vesicles. Recommended concentration of ab121685 1-4 µg/ml. Cells treated with PFA/Triton X-100.
  • ab121685 at 1/25 dilution staining ZNF750 in Paraffin-embedded Human Vagina tissue by Immunohistochemistry.

Anti-ZNF750 antibody (ab121685)参考文献

ab121685 has not yet been referenced specifically in any publications.

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