概述

  • 产品名称
    Anti-ZNF653抗体
  • 描述
    兔多克隆抗体to ZNF653
  • 宿主
    Rabbit
  • 经测试应用
    适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    antigen sequence: NVNCLKNVVI WYEDHKHRCP YEPHLAELDP TFGLYTTAVW QCEAGHRYFQ DLHSPLKPLS DSDPDSDKVG NGLVAGSSDS SSSGS, corresponding to amino acids 119-203 of Human ZNF653.

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • 阳性对照
    • Human cerebral cortex tissue; RT 4 and U 251 MG lysate.

性能

应用

Our Abpromise guarantee covers the use of ab121769 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/250 - 1/500.

靶标

  • 功能
    Transcriptional repressor. May repress NR5A1, PPARG, NR1H3, NR4A2, ESR1 and NR3C1 transcriptional activity.
  • 组织特异性
    Highly expressed in testis, cerebellum, temporal lobe, hippocampus and the adrenal gland. Moderately expressed in spleen, uterus, thymus, pancreas, kidney, stomach and rectum.
  • 序列相似性
    Belongs to the krueppel C2H2-type zinc-finger protein family.
    Contains 5 C2H2-type zinc fingers.
  • 细胞定位
    Nucleus.
  • Information by UniProt
  • 数据库链接
    • 别名
      • 67 kDa zinc finger protein antibody
      • Zinc finger protein 653 antibody
      • Zinc finger protein Zip67 antibody
      • ZIP67 antibody
      • ZN653_HUMAN antibody
      • Znf653 antibody
      see all

    图片

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ZNF653 antibody (ab121769)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ZNF653 antibody (ab121769)
      ab121769 at 1/50 dilution staining ZNF653 in paraffin embedded Human cerebral cortex tissue by Immunohistochemistry.
    • Western blot - Anti-ZNF653 antibody (ab121769)
      Western blot - Anti-ZNF653 antibody (ab121769)
      All lanes : Anti-ZNF653 antibody (ab121769) at 1/250 dilution

      Lane 1 : RT 4 cell lysate
      Lane 2 : U 251 MG cell lysate
      Lane 3 : Human plasma lysate
      Lane 4 : Human liver tissue lysate
      Lane 5 : Human tonsil tissue lysate

      Developed using the ECL technique.

    文献

    ab121769 has not yet been referenced specifically in any publications.

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