概述

  • 产品名称Anti-ZNF589抗体
    参阅全部 ZNF589 一抗
  • 描述
    兔多克隆抗体to ZNF589
  • 经测试应用适用于: ICC/IF, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 39-183 of Human ZNF589 (Q86UQ0).

  • 阳性对照
    • RT4 and U-251 MG cell lysates; Human bone marrow tissue.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab121173 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use a concentration of 1 - 4 µg/ml.

Recommend PFA Fixation and Triton X-100 treatment

IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能May play a role in hematopoietic stem/progenitor cell differentiation. May play a role as a DNA binding-dependent transcriptional repressor.
  • 组织特异性Isoform 2 is widely expressed. Isoform 3 is only expressed in CD34(+) cells.
  • 序列相似性Belongs to the krueppel C2H2-type zinc-finger protein family.
    Contains 4 C2H2-type zinc fingers.
    Contains 1 KRAB domain.
  • 结构域The KRAB domain mediates interaction with TRIM28.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • KRAB zinc finger protein SZF1 1 antibody
    • Stem cell zinc finger protein 1 antibody
    • SZF1 antibody
    • Zinc finger protein 589 antibody
    • ZN589_HUMAN antibody
    • ZNF589 antibody
    • ZNP589 antibody
    see all

Anti-ZNF589 antibody 图像

  • Immunofluorescent staining of Human cell line A-431 shows positivity in nuclei and cytoplasm. Recommended concentration of ab121173 1-4 µg/ml. Cells treated with PFA/Triton X-100.
  • All lanes : Anti-ZNF589 antibody (ab121173) at 1/250 dilution

    Lane 1 : RT4 cell lysate
    Lane 2 : U-251 MG cell lysate
    Lane 3 : Human Plasma lysate
    Lane 4 : Human Liver lysate
    Lane 5 : Human Tonsil lysate

    Developed using the ECL technique
  • ab121173 at 1/100 dilution staining ZNF589 in Paraffin-emebedded Human bone marrow tissue by Immunohistochemistry.

Anti-ZNF589 antibody (ab121173)参考文献

ab121173 has not yet been referenced specifically in any publications.

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