概述

  • 产品名称Anti-ZNF364抗体
    参阅全部 ZNF364 一抗
  • 描述
    兔多克隆抗体to ZNF364
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide derived from a region encoded by C terminal amino acids 254-303 (IVPWLELHDT CPVCRKSLNG EDSTRQSQST EASASNRFSN DSQLHDRWTF) of Human ZNF364

  • 阳性对照
    • HepG2 cell lysate

性能

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应用

Our Abpromise guarantee covers the use of ab80432 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 34 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Acts as an E2-dependent E3 ubiquitin-protein ligase. May be involved in endocytic trafficking.
  • 组织特异性Expressed at extremely low levels in normal breast, prostate, lung, colon. Higher levels of expression are detected in heart, skeletal muscle, testis as well as in breast and prostate cancer cells.
  • 通路Protein modification; protein ubiquitination.
  • 序列相似性Contains 1 RING-type zinc finger.
  • 翻译后修饰RING-type zinc finger-dependent and E2-dependent autoubiquitination.
  • 细胞定位Cytoplasm > cytosol. The GTP-bound form of RAB7A recruits RNF115 from the cytosol onto late endosomes/lysosomes.
  • Information by UniProt
  • 数据库链接
  • 别名
    • BCA2 antibody
    • Breast cancer associated gene 2 antibody
    • CL469780 antibody
    • E3 ubiquitin-protein ligase RNF115 antibody
    • Rabring 7 antibody
    • RING finger protein 115 antibody
    • RN115_HUMAN antibody
    • RNF115 antibody
    • Zinc finger protein 364 antibody
    see all

Anti-ZNF364 antibody 图像

  • Anti-ZNF364 antibody (ab80432) at 1 µg/ml + HepG2 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 34 kDa
    Observed band size : 34 kDa

Anti-ZNF364 antibody (ab80432)参考文献

This product has been referenced in:
  • Nityanandam R & Serra-Moreno R BCA2/Rabring7 targets HIV-1 Gag for lysosomal degradation in a tetherin-independent manner. PLoS Pathog 10:e1004151 (2014). WB . Read more (PubMed: 24852021) »
  • Rodrigo-Brenni MC  et al. Cytosolic quality control of mislocalized proteins requires RNF126 recruitment to Bag6. Mol Cell 55:227-37 (2014). Human . Read more (PubMed: 24981174) »

See all 3 Publications for this product

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