概述

  • 产品名称
  • 描述
    山羊多克隆抗体to ZNF364
  • 经测试应用
    适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Dog
  • 免疫原

    Synthetic peptide:

    C-DQDNRANERGHQTH

    , corresponding to internal sequence amino acids 97-110 of Human ZNF364

  • 阳性对照
    • HEPG2 cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab52016 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明
    Peptide ELISA: Antibody detection limit dilution 1:32,000.
    WB: Use at a concentration of 0.3 - 1.0 µg/ml. Detects a band of approximately 35 kDa (predicted molecular weight: 34 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      Acts as an E2-dependent E3 ubiquitin-protein ligase. May be involved in endocytic trafficking.
    • 组织特异性
      Expressed at extremely low levels in normal breast, prostate, lung, colon. Higher levels of expression are detected in heart, skeletal muscle, testis as well as in breast and prostate cancer cells.
    • 通路
      Protein modification; protein ubiquitination.
    • 序列相似性
      Contains 1 RING-type zinc finger.
    • 翻译后修饰
      RING-type zinc finger-dependent and E2-dependent autoubiquitination.
    • 细胞定位
      Cytoplasm > cytosol. The GTP-bound form of RAB7A recruits RNF115 from the cytosol onto late endosomes/lysosomes.
    • Information by UniProt
    • 数据库链接
    • 别名
      • BCA2 antibody
      • Breast cancer associated gene 2 antibody
      • CL469780 antibody
      • E3 ubiquitin-protein ligase RNF115 antibody
      • Rabring 7 antibody
      • RING finger protein 115 antibody
      • RN115_HUMAN antibody
      • RNF115 antibody
      • Zinc finger protein 364 antibody
      see all

    Anti-ZNF364 antibody 图像

    实验方案

    Anti-ZNF364 antibody (ab52016)参考文献

    ab52016 has not yet been referenced specifically in any publications.

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